·综述·老年患者术后谵妄的研究进展罗云根1,2,曹江北1∗(1中国人民解放军总医院第一医学中心麻醉科,北京100853;2解放军医学院,北京100853)【摘要】术后谵妄(POD)是手术后一种常见的急性中枢神经系统综合征。由于生理机能的减退,老年人较儿童和成年人更易发生POD,且POD严重影响着老年患者的术后转归。随着社会的老龄化,老年患者手术量每年递增,POD的临床研究已成为麻醉学领域的热点问题之一。本文从风险预测、预后评估、预防策略、治疗方案4个方向对POD的临床研究进展进行综述,以期为老年POD的临床防治工作提供依据。【关键词】老年人;术后谵妄;预后【中图分类号】R614.1【文献标志码】A【DOI】10.11915/j.issn.1671-5403.2023.10.167收稿日期:2022-12-05;接受日期:2023-03-06基金项目:国家重点研发计划(2018YFC2001900)通信作者:曹江北,E-mail:caojiangbei@301hospital.com.cnResearchprogressonpostoperativedeliriuminelderlypatientsLuoYungen1,2,CaoJiangbei1∗(1DepartmentofAnesthesiology,FirstMedicalCenter,ChinesePLAGeneralHospital,Beijing100853,China;2MedicalSchoolofChinesePLA,Beijing100853,China)【Abstract】Postoperativedelirium(POD)isacommonacutecentralnervoussystemsyndromeaftersurgery.Duetothephysiologicaldegeneration,PODoccursmorefrequentlyamongtheelderlypatientsthanamongthechildrenandadultsandhasseriousimpactontheirpostoperativeoutcomes.ThepopulationagingandtheincreasingannualvolumeofproceduralsperformedontheelderlypatientshavecausedPODtobecomeoneofthemostpopularissuesinthefieldofanesthesiology.Inthisarticle,wereviewedtherecentclinicalstudiesonPODinfourrespects:riskprediction,prognosisassessment,preventionstrategiesandtreatmentprotocols,withaviewtoprovidingabasisforitsclinicalpreventionandtreatmentamongtheelderly.【Keywords】aged;postoperativedelirium;prognosisThisworkwassupportedbytheNationalKeyResearchandDevelopmentProgramofChina(2018YFC2001900).Correspondingauthor:CaoJiangbei,E-mail:caojiangbei@301hospital.com.cn全国第七次人口普查公报发布数据:截止到2020年11月1日零时,我国65岁及以上人口达到19064万人,占总人口比例的13.50%。这一比例在10年间已上升4.63%,随着我国老龄化趋势的加剧及医疗水平的不断提升,老年患者手术数量也在逐年增加,...