·36·医药前沿2024年3月第14卷第9期论著急性脑梗死患者颈动脉斑块危险因素分析陈桂林(临沂市妇幼保健院神经内科山东临沂276000)【摘要】目的:探讨急性脑梗死患者颈动脉斑块的相关危险因素。方法:选取2021年7月—2023年7月临沂市妇幼保健院神经内科收治的急性脑梗死患者97例为研究对象,根据颈动脉超声检查结果将无斑块患者纳入无斑块组(n=35),斑块不稳定患者纳入不稳定组(n=28),斑块稳定患者纳入稳定组(n=34)。统计上述患者的临床资料、实验室检验结果等,采用Logistic回归分析探讨急性脑梗死患者颈动脉斑块的危险因素。结果:单因素分析结果显示,不稳定组和稳定组总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、胱抑素C(Cys-C)及体质量指数(BMI)均高于无斑块组,差异有统计学意义(P<0.05);Logistic回归分析结果显示,TC>5.2mmol·L−1、LDL-C>4.14mmol·L−1、Cys-C>1.09mg·L−1是急性脑梗死患者颈动脉斑块形成的危险因素(P<0.05)。结论:TC>5.2mmol·L−1、LDL-C>4.14mmol·L−1、Cys-C>1.09mg·L−1是急性脑梗死患者颈动脉斑块形成的主要危险因素。【关键词】急性脑梗死;颈动脉斑块;稳定性;危险因素【中图分类号】R743【文献标识码】A【文章编号】2095-1752(2024)09-0036-03AnalysisofriskfactorsforcarotidarteryplaquesinpatientswithacutecerebralinfarctionCHENGuilinDepartmentofNeurology,LinyiMaternalandChildHealthHospital,Linyi,Shandong276000,China【Abstract】ObjectiveToexploretherelatedriskfactorsofcervicalarteryplaqueinpatientswithacutecerebralinfarction.Methods97patientswithacutecerebralinfarctionadmittedtotheDepartmentofNeurologyofLinyiMaternityandChildHealthHospitalfromJuly2021toJuly2023wereselectedastheresearchobjects.Accordingtotheresultsofcervicalarteryultrasoundexamination,patientswithoutplaqueswereincludedinthenon-plaquegroup(n=35),patientswithunstableplaqueswereincludedintheunstablegroup(n=28),andpatientswithstableplaqueswereincludedinthestablegroup(n=34).Theclinicaldataandlaboratorytestresultsoftheabovepatientswerestatisticallyanalyzed,andlogisticregressionanalysiswasusedtoexploretheriskfactorsofcervicalarteryplaqueinpatientswithacutecerebralinfarction.ResultsTheresultsofunivariateanalysisshowedthatthelev...