10第25卷第2期2023年2月辽宁中医药大学学报JOURNALOFLIAONINGUNIVERSITYOFTCMVol.25No.2Feb.,2023当归补血汤研究进展马艳春,胡建辉,段莹,范楚晨,冯天甜,王旭,吴修红,吴文轩(黑龙江中医药大学,黑龙江哈尔滨150040)基金项目:国家自然科学基金项目(82174274)作者简介:马艳春(1972-),女,黑龙江哈尔滨人,研究员,博士,研究方向:方剂配伍规律及药效物质基础研究。摘要:当归补血汤记载于《内外伤辨惑论》,为金元四大家之一的李东垣所创,是益气补血的代表方,方中仅有两味药物黄芪和当归,两者配伍比例5∶1,经现代研究发现此配伍比例能够使当归补血汤中的活性成分含量最高,并且药理作用也得到增强。在国内和国外学者的研究中发现,当归补血汤的药理作用有促进造血功能、调节免疫、防治骨科疾病、抗纤维化、抗肿瘤等。关键词:当归补血汤;配伍比例;化学成分;药理作用;综述中图分类号:R28文献标志码:A文章编号:1673-842X(2023)02-0010-04ResearchProgressofDangguiBuxueDecoction(当归补血汤)MAYanchun,HUJianhui,DUANYing,FANChuchen,FENGTiantian,WANGXu,WUXiuhong,WUWenxuan(HeilongjiangUniversityofTraditionalChineseMedicine,Harbin150040,Heilongjiang,China)Abstract:DangguiBuxueDecoction(当归补血汤)isrecordedinthetheoryofinternalandexternalinjury.ItwascreatedbyLIDongyuan,oneofthefourmastersofJinandYuanDynasties.ItisarepresentativeprescriptionforsupplementingQiandtonifyingblood.Thereareonlytwoherbsintheprescription,Huangqi(AstragaliRadix)andDanggui(AngelicaeSinensisRadix).ThecompatibilityratioofHuangqi(AstragaliRadix)andDanggui(AngelicaeSinensisRadix)is5∶1.Throughmodernresearch,itisfoundthatthiscompatibilityratiocanmakethecontentofactiveingredientsinDangguiBuxueDecoctionhighest,andthepharmacologicaleffectisalsoenhanced.InthestudyofdomesticandforeignscholarsfoundthatthepharmacologicaleffectsofDangguiBuxueDecoctioncanpromotehematopoieticfunction,regulateimmunity,preventorthopedicdiseases,anti-fibrosis,anti-tumor,etc.Keywords:DangguiBuxueDecoction(当归补血汤);proportionofcompatibility;chemicalconstituents;pharmacologicalaction;review当归补血汤是金元时期四大家之一李东垣所创的方剂,它...