第25卷第2期2013年3月肝胆胰外科杂志JournalofHepatopancreatobiliarySurgeryVO1.25NO.2Mar.2013泰绫联合胶原蛋白海绵在肝切除术中的临床应用徐琦,高静涛,秦建伟,李智平,李庆怀(解放军第一医院肝胆外科、兰州军区肝胆外科中心,甘肃兰州730030)[摘要]目的探讨泰绫联合胶原蛋白海绵在肝切除断面的止血、防漏效果。方法随机将51例择期行肝部分切除术的患者分为治疗组和对照组,治疗组肝断面处理中使用泰绫联合胶原蛋白海绵,对照组不使用任何止血材料,比较两组术后24、48、72h腹腔引流量、引流管放置时问及创面发生渗血、胆漏的几率。结果治疗组术后腹腔引流量明显少于对照组,拔管时间缩短,创面渗血、胆漏发生率低于对照组,两组问差异有统计学意义(尸<0.05)。结论泰绫联合胶原蛋白海绵在肝切除术中具有安全、可靠的止血、防胆漏效果,能显著减少术后腹腔引流量,缩短腹腔引流时间。[关键词]肝切除术;断面处理;泰绫;胶原蛋白海绵[中图分类号]R619[文献标识码]A[文章编号]1007—1954(2013)0109—03TheclinicalapplicationofTailingcombinedwithcollagenspongeinhepatectomyXUai,GAOJing—tao.QINJian—weiela1.DepartmentofHepatobiliarySurgery.theFtrStHospitalofPLA,Lanzhou730030,ChinaobjectiveToinvestigatetheeffectofhemostasisandbile—leakagepreventionbyTailingcombinedwithcollagenspongewhichusedinhepatectomy.MethodsFifty—onepatientsundergoingpartialhepatectomywererandomlydividedintotWOgroups,treatmentgroupandcontrolgroup.Liver—sectionsweretreatedwithTailingandcollagenspongeinthetreatmentgroup,andnonthingwasusedinthecontrolgroup.Theabdominaldrainageat24h,48h,72hofpostoperation,extubationtimeandincidenceofhemorrhageandbileleakagewerecompared.ResultsTheabodominaldrainageandextubationtimeoftreatmentgroupweresignificantlylessthanthatofcontrolgroup.Theincidenceofhemorrhageandbileleakageintreatmentgroupwaslowerthanthatincontrolgroup.Thedifferencebetweentwogroupswasstatisticallysignificant(P<0.O5).ConclusionTheapplicationofTailingcombinedwithcollagenspongeinhepatectomyhasasafeandreliableeffectonhemostasisandbile—leakageprevention.Itcansignificantlyreducetheabdominaldrainageofpostoperation,andshortentheextubationtime.hepat...