LMR1LMR2DDR1DDR2LMR3CCK4/PTK7SuRTK106ROSLTKIRRMERRONRYKFLT1FLT4Tie1ARGTXKFRKFerCTKSRMEphA2EphA10EphA3EphA5EphA7EphA6EphA4EphA8EphB6TYRO3/SKYACKFESTNK1KitTie2CSFR/FMSKDRFLT3Pyk2BlkBtkBMX/ETKAblJak1Jak2Tyk2SykPDGFRβEphB4EphB2EphB3EphB1Zap-70HCKLynLCKSrcYesFynEGFRHER2HER3TrkATrkCTrkBMetINS-RIGF-IRFGFR3FGFR2FGFR1FGFR4ALKRetROR2ROR1FAKMUSKAxlTecCskBrkFGREphA1HER4PDGFRαJak3ItkReceptorTyrosineKinasesCytoplasmicTyrosineKinasesReceptor&CytoplasmicTyrosineKinases©2003-2008CellSignalingTechnology,Inc.Tyrosine_Kinases.ai•revisedSeptember2005www.cellsignal.comDirectStimulatoryModificationKinasePhosphataseCaspaseReceptorCyclin,pro-apoptoticEnzymepro-survivalGAP/GEFGTPaseG-protein,ribosomalsubunitTranscriptionFactorTranscriptionalStimulationTranscriptionalInhibitionTranslocationSeparationofSubunitsorCleavageProductsJoiningofSubunitsDirectInhibitoryModificationMultistepStimulatoryModificationMultistepInhibitoryModificationTentativeStimulatoryModificationTentativeInhibitoryModificationSignalingPathwaysKeywww.cellsignal.com©2003-2010CellSignalingTechnology,Inc.AcetylaseDeacetylase
