[基金项目]国家重点研发计划项目(Y２０１７YFC１１２６０２).[第一作者]刘思腾(１９９８—),女,河南商丘人,在读硕士.研究方向:乳腺疾病的影像学诊断.EＧmail:１３９３７００５３４９＠１６３．com[通信作者]于湛,郑州大学第一附属医院放射科,４５００５２.EＧmail:１３６７３６６６６２２＠１２６．com[收稿日期]２０２３Ｇ０３Ｇ２２[修回日期]２０２３Ｇ０６Ｇ１０胸部影像学PlainspectralCTquantitativeparametersfordifferentialdiagnosisofbenignandmalignantbreastlesionsLIUSiteng,YUZhan∗,LIJinglin,WANGJiejie,YANGYunxiao(DepartmentofRadiology,theFirstAffiliatedHospitalofZhengzhouUniversity,Zhengzhou４５００５２,China)[Abstract]ObjectiveToobservethevalueofquantitativeparametersofplainspectralCTfordifferentialdiagnosisofbenignandmalignantbreastlesions．MethodsDataofchestspectralCTof１１０femalepatientswithspaceoccupyingbreastlesionswereretrospectivelyanalyzed,including５３malignantlesionsin５３cases(malignantgroup)and６０benignlesionsin５７cases(benigngroup)．SpectralCTplainquantitativeparameters,includingCTvalueofvirtualsingleenergylevelof４０—１００keV,effectiveatomicnumber(EffＧZ)andspectralcurveslope(λHU)werecomparedbetweenthetwogroups．Receiveroperatingcharacteristic(ROC)curvesweredrawn,andtheareasunderthecurve(AUC)werecalculatedtoevaluatetheefficacyofspectralCTplainquantitativeparametersCT４０keV,CT７０keV,EffＧZandλHUaloneandincombinationfordifferentialdiagnosisofbenignandmalignantbreastlesions．ResultsUnder４０—１００keV,inmalignantgroup,CTvaluesandEffＧZwerehigherbutλHUwaslowerthanthoseinbenigngroup(allP＜０００１)．AUCofCT４０keV,CT７０keV,EffＧZandλHUfordifferentiatingbenignandmalignantbreastlesionsalonewas０９０,０８０,０８７and０８７,respectively,ofthecombinationoftheabovefourwas０９１,withthesensitivityof８４９％,thespecificityof８８３％andtheaccuracyof８５０％．ConclusionPlainspectralCTquantitativeparameterscouldbeusedtoeffectivelydifferentiatebenignandmalignantbreastlesions．[Keywords]breastneoplasms;diagnosis,differential;tomography,XＧraycomputedDOI:１...
