中文科技期刊数据库（全文版）医药卫生25冠心病合并房颤抗凝、双联抗血小板治疗作用及体表心电图f波振幅研究梁弘宏武彩霞（通讯作者）张家口仁爱医院，河北张家口076450摘要：目的冠心病合并房颤抗凝、双联抗血小板治疗作用及体表心电图f波振幅研究。方法选取院中42例冠心病合并房颤患者，抽取时间为2019年8月至2020年1月，随机分组（对照、研究组），前组拟传统抗凝治疗，后组双联抗血小板治疗，观察两小组试验成果。结果有效率为研究组比对照组高，但体表心电图V1导联f波平均振幅，不良事件发生率低于对照组，P＜0.05。结论冠心病合并房颤治疗拟用双联抗血小板治疗在能提高临床疗效，大意义上解决体表心电图f波振幅得以恢复且用药安全，借鉴价值高。关键词：冠心病；房颤；抗凝；双联抗血小板；应用效果中图分类号：R4Studyonanticoagulationandf-waveamplitudeofsurfaceelectrocardiogramLANGHonghongWUCaixia（correspondingauthor）ZhangjiakouRen'aiHospital,HebeiZhangjiakou076450Abstract:Objective:TostudytheanticoagulantanddualantiplatelettherapyeffectsofcoronaryheartdiseasecombinedwithatrialfibrillationandtheamplitudeofsurfaceelectrocardiogramF-wave.Method:42patientswithcoronaryheartdiseasecombinedwithatrialfibrillationwereselectedfromthehospitalfromAugust2019toJanuary2020.Theywererandomlydividedintoacontrolgroupandastudygroup.Theformergroupreceivedtraditionalanticoagulanttherapy,whilethelattergroupreceiveddualantiplatelettherapy.Theexperimentalresultsofthetwogroupswereobserved.Theeffectiverateofthestudygroupwashigherthanthatofthecontrolgroup,buttheaverageamplitudeoftheV1leadfwaveonthebodysurfaceelectrocardiogramandtheincidenceofadverseeventswerelowerthanthoseofthecontrolgroup(P<0.05).Conclusion:Theuseofdualantiplatelettherapyforthetreatmentofcoronaryheartdiseasecombinedwithatrialfibrillationcanimproveclinicalefficacy,significantlysolvetheproblemofrestoringtheamplitudeofF-waveonthebodysurfaceelectrocardiogram,andensuremedicationsafety.Ithashighreferencevalue.Keywords:coronaryheartdisease;atrialfibrillation;anticoagulation;doubleantiplatelet;applicationeffect冠心病作为临床常见病，发病率较高，近些年人口老龄化速度的提升促使该病发...
