LILi，etal：ResearchProgressofAlginatePolysaccharideMolecularModifyingEnzymesJOURNALOFFOODSCIENCEANDBIOTECHNOLOGYVol.42Issue12023ReviewResearchProgressofAlginatePolysaccharideMolecularModifyingEnzymesLILi1，NINGLimin2，YAOZhong1，ZHUBenwei*1，XUHong1（1.CollegeofFoodScienceandLightIndustry,NanjingTechUniversity,Nanjing210009,China；2.SchoolofMedicineandHolisticIntegrativeMedicine,NanjingUniversityofChineseMedicine,Nanjing210023,China）Abstract：Asalinearpolysaccharide,alginatehasdifferentphysiologicalandbiochemicalcharacteristicsaccordingtoitsstructureandcomposition.Itholdsgreatapplicationvalueandpotentialinfood,medicineandcosmetics.Thesecharacteristicsofalginatearemainlycontrolledbytheactionofalginate-modifyingenzymessuchasalginatelyase,mannuronanC5-epimerase,alginateacetylaseandalginatedeacetylase.Thisreviewmainlyintroducedthesynthesisofalginate-modifyingenzymesandthemechanismofalginatemodification,andsummarizedthesource,classification,structure,modeofactionandresearchprogressofseveralalginatemodifyingenzymes.TheemphasiswaslaidontheresearchprogressofalginatelyaseandmannuronanC5-epimerase.Andwealsoprospectedthefuturedevelopmentofrelatedresearch,providingreferenceforthefurtherdevelopmentandapplicationofalginateanditsrelatedmodifyingenzymes.Keywords:alginatepolysaccharide,alginatemodification,alginatelyase,mannuronanC5-epimerase摘要：褐藻胶作为一种线性多糖根据其结构和组成差异具有不同的生理生化特性，在食品、医药和化妆品等领域有着巨大的应用价值和潜力。褐藻胶的这些特性主要通过褐藻胶修饰酶如褐藻胶裂解酶、甘露聚糖C5差向异构酶、褐藻胶乙酰化酶和褐藻胶脱乙酰化酶的作用控制。作者主要概述了褐藻胶修饰酶合成和修饰褐藻胶的作用机理，总结了几种褐藻胶修饰酶的来源、分类、结构、作用方式和研究进程，重点阐述了褐藻胶裂解酶和甘露聚糖C5差向异构酶的相关研究进展，并对相关研究的未来发展提出展望，可为进一步开发和应用褐藻胶及其相关修饰酶提供借鉴和参考。关键词：褐藻胶多糖；褐藻胶修饰；褐藻胶裂解酶；甘露聚糖C5差向异构酶中图分类号：Q55文章编号：1673-1689（2023）01-0018-22DOI：10.3969/j.issn.1673...
