2023年2月第30卷第2期腹腔镜阑尾切除术对急性阑尾炎患者术后疼痛程度、免疫应激反应及并发症的影响张琪,李明亮,贺铁刚(驻马店市正阳县人民医院普外科,河南驻马店463600)【摘要】目的探讨腹腔镜阑尾切除术对急性阑尾炎患者术后疼痛程度、免疫应激反应及并发症的影响。方法136例急性阑尾炎患者根据手术方案的不同分为对照组(开腹阑尾切除术)和观察组(腹腔镜阑尾切除术),比较两组的术后疼痛程度、免疫应激反应及并发症发生率。结果观察组术后1d、3d的VAS评分均低于对照组,术后并发症发生率低于对照组(P<0.05)。术后3d,两组的IgM、IgG、PA水平均低于术前,但观察组的血清IgM、IgG、PA水平均高于对照组(P<0.05)。结论与开腹阑尾切除术相比,腹腔镜阑尾切除术可明显减轻急性阑尾炎患者的术后疼痛程度及免疫应激反应,降低术后并发症发生率。【关键词】急性阑尾炎;开腹阑尾切除术;腹腔镜阑尾切除术中图分类号:R574.61文献标识码:Adoi:10.3969/j.issn.1674-4659.2023.02.0161ImpactofLaparoscopicAppendectomyonPostoperativePainDegree,ImmuneStressResponseandComplicationsinPa-tientswithAcuteAppendicitis//ZHANGQi,LIMingliang,HETiegang(DepartmentofGeneralSurgery,ZhengyangCountyPeople'sHospital,Zhumadian463600,China)[Abstract]ObjectiveToexploretheimpactoflaparoscopicappendectomyonpostoperativepaindegree,immunestressresponseandcomplicationsinpatientswithacuteappendicitis.Methods136patientswithacuteappendicitisweredividedintothecontrolgroup(openappendectomy)andtheobservationgroup(laparoscopicappendectomy)accordingtodifferentsurgicalschemes.Thepostoperativepaindegree,immunestressresponseandincidenceofcomplicationswerecomparedbetweenthetwogroups.ResultsTheVASscoresat1dand3daftersurgeryoftheobservationgroupwerelowerthanthoseofthecontrolgroup,andtheincidenceofpostoperativecomplicationswaslowerthanthatofthecontrolgroup(P<0.05).At3daysaftersurgery,thelevelsofIgM,IgGandPAinbothgroupswerelowerthanthosebeforesurgery,butthelevelsofserumIgM,IgGandPAoftheobservationgroupwerehigherthanthoseofthecontrolgroup(P<0.05).ConclusionsComparedwithopenappendectomy,laparoscopicappendectomycansignificantlyreducepostoperativepaindegreeandimmunestressrespons...