临床医学临床医学China&ForeignMedicalTreatment中外医疗2024NO.6中外医疗China&ForeignMedicalTreatment内镜下黏膜剥离术治疗消化道早期癌及癌前病变的临床效果章杰龙岩市第二医院消化内科，福建龙岩364000［摘要］目的探讨消化道早期癌及癌前病变患者给予内镜下黏膜剥离术治疗的效果。方法回顾性选取2021年1—12月龙岩市第二医院消化内科接受手术治疗的102例消化道早期癌及癌前病变患者的临床资料，按照临床手术干预方法分为两组，每组51例。对照组采取内镜下黏膜切除术治疗，观察组采取内镜下黏膜剥离术治疗。比较两组患者的手术切除情况、手术指标、并发症发生率和生活质量评分。结果治疗后，观察组的治愈性切除率为84.31%，整块切除率为96.08%，完整切除率为92.16%，均高于对照组的62.75%、78.43%、74.51%，差异有统计学意义（χ2=6.095、7.141、5.718，P均<0.05）。观察组的近期、远期并发症发生率均低于对照组，差异有统计学意义（P均<0.05）。观察组术后3、6、12个月的生活质量评分均高于对照组，差异有统计学意义（P均<0.05）。结论采取内镜下黏膜剥离手术治疗能够提高切除效果，降低并发症发生率，提高患者的生活质量。［关键词］消化道早期癌；癌前病变；黏膜剥离术；临床效果［中图分类号］R735［文献标识码］A［文章编号］1674-0742（2024）02(c)-0057-05ClinicalEffectofEndoscopicMucosalDissectionintheTreatmentofEarlyGastrointestinalCancerandPrecancerousLesionsZHANGJieDepartmentofGastroenterology,LongyanSecondHospital,Longyan,FujianProvince,364000China[Abstract]ObjectiveToinvestigatetheeffectofendoscopicmucosaldissectioninpatientswithearlygastrointestinalcancerandprecancerouslesions.MethodsTheclinicaldataof102patientswithearlygastrointestinalcancerandpre⁃cancerouslesionswhoreceivedsurgicaltreatmentinthegastroenterologyDepartmentoftheSecondHospitalofLong⁃yanCityfromJanuarytoDecember2021wereretrospectivelyselectedanddividedintotwogroupsaccordingtoclini⁃calsurgicalinterventionmethods,with51casesineachgroup.Thecontrolgroupwastreatedwithendoscopicmucosalresection,andtheobservationgroupwastreatedwithendoscopicmucosaldissection.Thesurgicalresection,surgicalindexes,theincidenceofcomplicationsandqualityoflifescoreswerecomparedbetweenthetwogroupsofpatient...
