16上海医药2023年第44卷第17期(9月上)·药物临床·卡贝缩宫素联合卡孕栓对剖宫产术子宫收缩乏力产后出血的预防效果胡娟娟(赣州市妇幼保健院江西赣州341000)摘要目的:探究卡贝缩宫素联合卡孕栓对剖宫产术子宫收缩乏力产后出血的预防效果。方法:选取82例剖宫产后子宫收缩乏力产妇,随机分为两组,各41例。对照组采取卡贝缩宫素,观察组在此基础上加用卡孕栓。比较两组产后出血情况、恶露持续时间及不良反应。结果:观察组产后出血发生率及产后2、24h的出血量低于对照组,恶露持续时间短于对照组(P<0.05);两组不良反应比较,差异无统计学意义(P>0.05)。结论:剖宫产术子宫收缩乏力患者采用卡贝缩宫素联合卡孕栓治疗能改善产后出血状况,且不增加不良反应。关键词剖宫产子宫收缩乏力产后出血卡贝缩宫素卡孕栓不良反应中图分类号:R984;R714.41文献标志码:B文章编号:1006-1533(2023)17-0016-04引用本文胡娟娟.卡贝缩宫素联合卡孕栓对剖宫产术子宫收缩乏力产后出血的预防效果[J].上海医药,2023,44(17):16-19.PreventiveeffectofcarbetocincombinedwithcarboprostmethylatesuppositoryonpostpartumhemorrhageduetouterineatonyduringcesareansectionHUJuanjuan(GanzhouMaternalandChildHealthCareHospital,Ganzhou341000,China)ABSTRACTObjective:Toexplorethepreventiveeffectofcarbetocincombinedwithcarboprostmethylatesuppositoryonpostpartumhemorrhageduetouterineatonyaftercesareansection.Methods:Eighty-twowomenwithuterineatonyaftercesareansectionwererandomlydividedintoacontrolgroupandanobservationgroupwith41caseseach.Thecontrolgroupwastreatedwithcarbetocin,andtheobservationgroupwastreatedwithbothcarbetocinandcarboprostmethylatesuppository.Thepostpartumhemorrhage,durationoflochiaandadversereactionswerecomparedbetweenthetwogroups.Results:Theincidenceofpostpartumhemorrhageandtheamountofhemorrhageatpostpartum2and24hourswerelessandthedurationoflochiawasshorterintheobservationgroupthanthecontrolgroup(P<0.05).Therewerenostatisticallysignificantdifferencesinadversereactionsbetweenthetwogroups(P>0.05).Conclusion:Thecombinationtreatmentcanimprovethepostpartumhemorrhageinpatientswithuterineatonyaftercesareansectionwithouttheincreaseofadversereactions.KEYWORDScesare...