334·临床研究·局部进展期肾癌患者术后预后列线图的建立与验证李飞，问晓东，柴红强，吴明，庞磊（山西医科大学第五临床医学院泌尿外科，山西太原030012）DevelopmentandvalidationofaprognosticnomogramforlocallyadvancedrenalcellcarcinomapatientsaftersurgeryLIFei,WENXiaodong,CHAIHongqiang,WUMing,PANGLei(DepartmentofUrology,The5thClinicalMedicalCollege,ShanxiMedicalUniversity,Taiyuan030012,China)ABSTRACT:ObjectiveToconstructanomogramsurvivalpredictionmodelforpatientswithlocallyadvancedrenalcellcarcinomabasedonSEERdatabase(n=7893),soastoprovidereferenceforfutureprognosisstudy.MethodsCasedataweredownloadedfromtheSEERdatabase,anddividedintotheexperimentalgroupandvalidationgroupwitharatioof7:3bysimplerandomization.Theclinicalinformationwasanalyzed,independentriskfactorsinfluencingprognosiswerescreened,andtheoverallsurvival(OS)andtumor-specificsurvival(CSs)weremapped.Modelperformancewasevaluatedusingconsistencyindex,areaunderthereceiveroperatingcharacteristiccurve(AUC),internalandexternalvalidation,andcalibrationcurves.ResultsPatients'age,tumorsize,diseaseprogressiontpye,TNMstage,numberofpositivelymphnodes,maritalstatusandpathologicaltypeweresignificantlycorrelatedwithOSandCSS(P
