http://jmurology．xjtu．edu．cn;zgmnwk．cug．top收稿日期:２０２３Ｇ０３Ｇ２６修回日期:２０２３Ｇ０７Ｇ２８基金项目:国家自然科学基金项目(No．８２０６０１３７)通信作者:刘建和,主任医师,硕士生导师.EＧmail:９７２３０６００＠qq．com作者简介:杨斌,硕士研究生在读,住院医师.研究方向:泌尿系结石的诊断、治疗、预防的研究.EＧmail:clmy２１yangbin＠１６３．com临床研究经皮肾镜取石术分期治疗结石性脓肾临床效果的Meta分析杨斌,耿尔康,万川平,牛愿坚,李玉志,刘建和(昆明医科大学第二附属医院泌尿外科,云南昆明６５０１０６)StageＧbyＧstageclinicaloutcomesofpercutaneousnephrolithotomyforcalculouspyonephrosis:aMetaＧanalysisYANGBin,GENGErkang,WANChuanping,NIUYuanjian,LIYuzhi,LIUJianhe(DepartmentofUrology,TheSecondAffiliatedHospitalofKunmingMedicalUniversity,Kunming６５０１０６,China)ABSTRACT:ObjectiveToidentifythebestsurgicaltreatmentforpatientswithcalculouspyonephrosisbyevaluatingtheclinicaleffectivenessofpercutaneousnephrolithotripsy(PCNL)instageⅠ,percutaneousnephrostomy(PCN)instageⅠ,andpercutaneousnephrolithotripsyinstageⅡ．MethodsForpublicationspublishedbetweenJan．２０１２andOct．２０２２,wethoroughlyexaminedthedatabasesofPubMed,CochraneLibrary,WebofScience,EMBASE,CNKI,Wanfang,andVIP．Wethenchosedtheliteraturebasedontheinclusionandexclusioncriteria．Afterdatawereretrievedandliteraturequalitywasassessed,ReviewManagersoftware(RevMan５．４．３,CochraneCollaboration,Oxford,UK)wasutilizedtoMetaＧanalysis．ResultsOutof６８８participantsacross１０５researches,wechosed１１trials．Amongthem,３４１patientsreceivedbothstageⅠPCNandstageⅡPCNL(hereinafterreferredtoasphaseⅡPCNL),while３４７patientsreceivedstageⅠPCNL．AccordingtotheresultsoftheMetaＧanalysis,therewasnodiscernibledifferencebetweenstageⅠPCNLandstageⅡPCNLintermsofstoneclearancerate(P＝０．９５),operationduration(P＝０．４８),postoperativesepticshock(P＝０．３６),orperirenaleffusioninfection(P＝０．２７)．ThereweresignificantdifferencesbetweenstageⅠPCNLandstageⅡPCNLinfever(P＝０．０３),indwellingnephrostomytubetime(P＝０．０１),ho...
