临床医学研究与实践2023年10月第8卷第28期ClinicaleffectoftransurethralresectionofbladdermucosacombinedwithcelecoxibinthetreatmentofintestinalcystitisglandularisJIJunpeng1,LIHuibing2,LIHuiping1,CAOQiong1,SHIWenhong1(1.LuoyangDongfangPeople'sHospital/theThirdAffiliatedHospitalofHenanUniversityofScienceandTechnology,Luoyang471003;2.theFirstAffiliatedHospitalofHenanUniversityofScienceandTechnology,Luoyang471003,China)ABSTRACT:ObjectiveToinvestigatetheefficacyandsafetyoftransurethralresectionofbladdermucosacombinedwithcelecoxibinthetreatmentofintestinalcystitisglandularis(CG).MethodsAtotalof53patientswithintestinalCGfromJanuary2019toJune2021wereselectedastheresearchobjectsanddividedintoexperimentalgroup(n=27,treatedwithtransurethralresectionofbladdermucosacombinedwithcelecoxib)andcontrolgroup(n=26,treatedwithtransurethralresectionofbladdermucosa)accordingtodifferenttreatmentmethods.Theclinicalsymptomscores,postoperativerecurrenceandclinicalefficacywerecomparedbetweenthetwogroups.ResultsAt13,6,9and12monthsafteroperation,theclinicalsymptomscoreoftheexperimentalgroupwaslowerthanthatbeforeoperation(P<0.05);at1,3,6,9and12monthsafteroperation,theclinicalsymptomscoreoftheexperimentalgroupwaslowerthanthatofthecontrolgroup(P<0.05).Thepostoperativerecurrencerateoftheexperimentalgroupwassignificantlylowerthanthatofthecontrolgroup(P<0.05).Theoperationofthetwogroupswassuccessfullycompleted,andnocomplicationssuchasbladderperforation,perioperativehemorrhageandureteralstrictureoccurred.Thetotaleffectiverateoftreatmentintheexperimentalgroupwassignificantlyhigherthanthatinthecontrolgroup(P<0.05).ConclusionTransurethralresectionofbladdermucosacombinedwithcelecoxibhasagoodclinicaleffectinthetreatmentofintestinalCG,whichcanreducetherecurrencerateofthedisease.KEYWORDS:intestinalcystitisglandularis;transurethralresectionofbladdermucosa;celecoxib经尿道膀胱黏膜电切术联合塞来昔布治疗肠型腺性膀胱炎的临床效果姬俊鹏1，李会兵2，李会平1，曹琼1，史文红1（1.洛阳市东方人民医院/河南科技大学第三附属医院，...
