OSD1Fuzhou331800,China(临床工程）·论著·.1183.临床医学工程星2023年9月第30卷第9期经鼻高流量氧疗对重症肺炎合并呼吸衰竭患者血气分析指标及肺功能的影响姜秀明，周官发，胡雷（江西省抚州市东乡区人民医院重症医学科，江西抚州331800)【摘要】目的探讨经鼻高流量氧疗对重症肺炎合并呼吸衰竭患者血气分析指标及肺功能的影响。方法将我院收治的68例重症肺炎合并呼吸衰竭患者随机分为两组各34例。对照组给予普通高流量面罩吸氧，观察组给予经鼻高流量氧疗。比较两组的血气分析指标、肺功能、改V60无创通气率、改气管插管率。结果治疗后，观察组HCO；、SaO2、PaO2、MVV、FVC、PEF、DLco值高于对照组，PaCO2低于对照组（P<0.05）。两组的改气管插管率比较无统计学差异（P>0.05)；观察组改V60无创通气率低于对照组（P<0.05。结论经鼻高流量氧疗可有效调节重症肺炎合并呼吸衰竭患者的血气分析指标，改善肺功能。【关键词】重症肺炎；呼吸衰竭；经鼻高流量氧疗；血气分析；肺功能中图分类号：R563.1文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.09.1183InfluenceofNasalHighFlowOxygenTherapyonBloodGasAnalysisIndicatorsandPulmonaryFunctioninPatientswithSeverePneumoniaComplicatedwithRespiratoryFailureJIANGXiuming,ZHOUGuanfa,HULei(IntensiveCareUnita,HULei(IntensiveCareUnit,DongxiangDistrictPeople'sH[Abstract]ObjectiveToexploretheinfluenceofnasalhighflowoxygentherapyonbloodgasanalysisindicatorsandpulmonaryfunctioninpatientswithseverepneumoniacomplicatedwithrespiratoryfailure.Methods68patientswithseverepneumoniacomplicatedwithrespiratoryfailureadmittedtoourhospitalwererandomlydividedintotwogroups,with34casesineachgroup.Thecontrolgroupreceivedordinaryhighflowmask,andtheobservationgroupreceivednasalhighflowoxygentherapy.Thebloodgasanalysisindicators,pulmonaryfunction,andtheratesofV60non-invasiveventilationandtrachealintubationofthetwogroupswerecompared.ResultsAftertreatment,theHCOs,SaO2,PaO2,MVV,FVC,PEFandDLcooftheobservationgroupwerehigherthanthoseofthecontrolgroup,andPaCO2waslowerthanthatofthecontrolgroup(P<0.05).Nostatisticaldifferencewasfoundinthetrachealintubationratebetweenthetwogroups(P>0.05).TheV60non-invasiveventilationrateoftheobservationgro...
