·综述.388JSurgConceptsPract2023,Vol.28,No.4近端胃切除抗反流消化道重建方式的研究进展孙强,姚骏,张鑫,杜杉珊²综述,王伟军1审校(1.海军军医大学附属长征医院胃肠外科,上海200003;2.上海市闵行区古美社区卫生服务中心针伤科,上海201100)[摘要]近端胃癌在中国及部分亚洲国家的发病率呈逐年上升趋势。手术是该疾病最有效、最常用的治疗方式。传统全胃切除术具有较好的根治效果,但术后难以避免营养代谢障碍、生活质量下降等并发症发生。近年来临床开展的近端胃切除术在切除肿瘤组织的同时,保留部分胃组织,有利于改善病人术后营养状况。然而近端胃切除术中破坏食管括约肌和His角,引起残胃反酸、反流,导致反流性食管炎,同样也影响病人的生活质量。为解决反流的问题,临床医师探索不同消化道重建术式,目前有报道的消化道重建方法很多,各有优劣。本文结合相关文献和临床新进展,列举目前常用消化道重建方法,总结其术后生活质量、生存结局相关文献资料,以供临床医师参考和选择。关键词:近端胃癌;近端胃切除术;反流性食管炎;消化道重建中图分类号:R735.2;R571文献标志码:C文章编号:1007-9610(2023)04-0388-06D01:10.16139/j.1007-9610.2023.04.017ResearchprogressofantirefluxdigestivetractreconstructionforproximalgastrectomySUNQiang',YAOJun',ZHANGXin',DUShanshan',WANGWeijun'1.DepartmentofGastrointestinalSurgery,ChangzhengHospital,NavalMilitaryMedicalUniversity,Shanghai200003,China;2.DepartmentofAcupunctureandTraumatology,GumeiCommunityHealthServiceCenterofMinhangDistrict,Shanghai201100,China[Abstract]TheincidencerateofproximalgastriccancerinChinaandsomeAsiancountriesisincreasingyearbyyear.Surgeryisthemosteffectiveandcommonlyusedtreatmentforproximalgastriccancer.Traditionaltotalgastrectomyhasagoodcurativeeffect,butitscomplications,suchasdystrophicmetabolismanddecreasedqualityoflife,limiteditsuse.Inrecentyears,theproximalgastrectomycarriedoutclinicallycanremovetumortissueandpreservepartofgastrictis-sue,whichisconducivetoimprovingthepostoperativenutritionalstatusofpatients.However,duringproximalgastrectomy,theesophagealsphincterandHisangleweredamaged,resultinginresidualgastricacidrefluxandgastroesophagealreflux,resultinginrefluxesophagiti...