SYSTEMSMEDICINE系统医学系统医学2023年9月第8卷第17期·内科研究·经鼻高流量吸氧对重症肺炎合并呼吸衰竭患者的治疗作用张於,单敏捷北京燕化医院呼吸内科,北京102500[摘要]目的研究经鼻高流量吸氧方式对于重症肺炎合并呼吸衰竭患者的治疗效果。方法选取2021年12月—2023年6月北京燕化医院收治的重症肺炎合并呼吸衰竭患者110例,采用随机数表法分为研究组(经鼻高流量吸氧)和对照组(普通面罩吸氧),单组55例,分析不同吸氧方式的治疗效果(体征指标、住院时间、插管率)。结果入院48h,研究组体征指标优于对照组,差异有统计学意义(P<0.05)。研究组住院时间(12.51±1.68)d、插管率1.82%(1/55),低于对照组住院时间(17.52±2.14)d、插管率14.54%(8/55),差异有统计学意义(t=19.108,χ2=5.930,P<0.05)。结论对重症肺炎合并呼吸衰竭患者进行经鼻高流量吸氧治疗,可改善患者体征指标,降低住院时间、插管率。[关键词]经鼻高流量吸氧;重症肺炎合并呼吸衰竭;体征指标[中图分类号]R563[文献标识码]A[文章编号]2096-1782(2023)09(a)-0129-03TherapeuticEffectofTrans-nasalHigh-flowOxygenInhalationonPa⁃tientswithSeverePneumoniaCombinedwithRespiratoryFailureZHANGYu,SHANMinjieDepartmentofRespiratoryMedicine,BeijingYanhuaHospital,Beijing,102500China[Abstract]ObjectiveTostudythetherapeuticeffectoftrans-nasalhigh-flowoxygeninhalationonpatientswithse‑verepneumoniacombinedwithrespiratoryfailure.Methods110patientswithseverepneumoniacomplicatedwithre‑spiratoryfailureadmittedtoBeijingYanhuaHospitalfromDecember2021toJune2023wereselectedandrandomlydividedintoastudygroup(nasalhighflowoxygeninhalation)andacontrolgroup(ordinarymaskoxygeninhalation)usinganumbertablemethod,with55casesineachgroup.Thetreatmenteffectsofdifferentoxygeninhalationmeth‑ods(physicalsigns,hospitalizationtime,intubationrate)wereanalyzed.ResultsAfter48hofadmission,thephysicalindicatorsofthestudygroupwerebetterthanthoseofthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05).Thehospitalizationtime(12.51±1.68)d,intubationrate1.82%(1/55)ofthestudygroupwerelowerthanthoseofthecontrolgroup(17.52±2.14)d,andintubationrate4.54%(8/55),thedifferencewasstatisticallysigni...