医药前沿2024年2月第14卷第4期综述·45·富血小板血浆治疗疱疹后神经痛的现状研究鞠嫒1，文昌晖2（通信作者）（1贵州中医药大学研究生院贵州贵阳550002）（2贵州中医药大学第一附属医院皮肤科贵州贵阳550002）【摘要】带状疱疹是由潜伏在脊髓后根神经节中的水痘-带状疱疹病毒引起的急性感染性皮肤病，在机体免疫力降低时会导致病毒激活。疱疹后神经痛是急性带状疱疹感染最典型的后遗症，临床表现复杂多样，疼痛迁延难愈，当前疱疹后神经痛发生机制仍未知，且治疗方法有限，尚无明确统一方案。含有较高浓度血小板的富血小板血浆在治疗神经病理性疼痛的应用中，具有巨大前景。本文就富血小板血浆治疗疱疹后神经痛的研究进展进行综述，以期为临床治疗提供线索及新方案。【关键词】疱疹后神经痛；富血小板血浆；生长因子；发病机制【中图分类号】R752.1【文献标识码】A【文章编号】2095-1752（2024）04-0045-03Theresearchofplatelet-richplasmainthetreatmentofpostherpeticneuralgiaJUAi1,WENChanghui2(Correspondingauthor)1GraduateSchool,GuizhouUniversityofTraditionalChineseMedicine,Guiyang,Guizhou550002,China2DepartmentofDermatology,TheFirstAffiliatedHospitalofGuizhouUniversityofTraditionalChineseMedicine,Guiyang,Guizhou550002,China【Abstract】Herpeszosterisanacuteinfectiousskindiseasecausedbyvaricella-zosterviruslatentinthedorsalrootganglionofthespinalcord.Whenthebody'simmunityisreduced,itcausesthevirustoactivate.Postherpeticneuralgiaisthemosttypicalsequelaeofacuteherpeszosterinfection.Theclinicalmanifestationsarecomplexanddiverse,andthepainisdifficulttoheal.Atpresent,themechanismofpostherpeticneuralgiaisstillunknown,andthetreatmentmethodislimited.Thereisnoclearandunifiedplan.Platelet-richplasmacontaininghighconcentrationsofplateletshasgreatprospectsinthetreatmentofneuropathicpain.Thearticleaimstoreviewtheresearchprogressofplatelet-richplasmainthetreatmentofpostherpeticneuralgia,inordertoprovidecluesandnewschemesforclinicaltreatment.【Keywords】Postherpeticneuralgia;Platelet-richplasma;Growthfactors;Pathogenesis疱疹后神经痛（postherpeticneuralgia,PHN）是带状疱疹病毒感染后最典型的后遗症。调查表明，带状疱疹患者在发病3个月后，60岁以下患者的P...
