·40·医药前沿2024年4月第14卷第11期综述非侵入方法评估肝硬化合并食管胃底静脉曲张及出血的研究进展王协揆1，张明香1,2（通信作者），王拱辰3（1辽宁中医药大学第一临床学院辽宁沈阳110033）（2沈阳市中医院消化内科辽宁沈阳110004）（3大连市公共卫生临床中心辽宁大连116113）【摘要】肝硬化合并食管胃底静脉曲张及出血评估的金标准是食管、胃、十二指肠镜检查，临床也可通过肝静脉压力梯度测定间接判断临床显著性门静脉高压，但这两种诊断方法均为有创操作且价格昂贵、患者依从性差。近几年国内外指南和专家共识也推荐非侵入检查评估食管胃底静脉曲张及出血，本文对无创检验、检查、评分模型、人工智能等非侵入方法评估食管胃底静脉曲张及出血研究进展进行综述。【关键词】综述；肝硬化；食道胃静脉曲张；出血；非侵入方法【中图分类号】R657.3【文献标识码】A【文章编号】2095-1752（2024）11-0040-06Researchprogressofnon-invasivemethodstoevaluatelivercirrhosiscomplicatedwithesophagealandgastricfundalvarixandbleedingWANGXiekui1,ZHANGMingxiang1,2(Correspondingauthor),WANGGongchen31FirstClinicalCollege,LiaoningUniversityofTraditionalChineseMedicine,Shenyang,Liaoning110033,China2DepartmentofGastroenterology,ShenyangTraditionalChineseMedicineHospital,Shenyang,Liaoning110004,China3DalianPublicHealthClinicalCente,Dalian,Liaoning116113,China【Abstract】Thegoldstandardfortheassessmentofesophagealandgastricfundalvarix(EGV)andbleedingincirrhoticpatientsisesophagogastroduodenoscopy.Clinically,significantportalhypertensioncanalsobeindirectlydeterminedbymeasuringhepaticvenouspressuregradient,butbothdiagnosticmethodsareinvasive,expensive,andpoorlycompliantforpatients.Inrecentyears,guidelinesandexpertconsensusbothdomesticallyandabroadhavealsorecommendednon-invasiveassessmentforEGVandbleeding.Thisarticlereviewstheresearchprogressonnon-invasivemethodsincludingnon-invasivetests,examinations,scoringmodels,artificialintelligence,fortheevaluationofEGVandbleeding.【Keywords】Review;Cirrhosis;Esophagealandgastricfundalvarix;Bleeding;Non-invasivemethods肝硬化食管胃静脉曲张（esophagealandgastricfundalvarix,EGV）和出血评估的金标准为食管、胃、十二指肠...
