论著冠状动脉钙化积分与冠心病介入术后近期预后的相关性张宏伟１李新国２∗(１．西安国际医学中心北院区老年心血管内科,陕西西安７１０１１９;２．延安大学咸阳医院心血管内科,陕西咸阳７１２０００)[摘要]【目的】探讨冠状动脉钙化积分(CCS)与冠心病(CAD)介入术后近期预后的相关性.【方法】１２０例接受冠状动脉介入治疗的CAD患者,均施行冠状动脉CT血管造影检查(CTA),计算CCS.院外随访６个月,记录主要不良心血管事件(MACE)发生情况及无MACE生存时间,据此,将患者分为预后不良组(n＝２７)及预后良好组(n＝９３).分析CCS与患者预后不良的关系及预测价值.【结果】预后不良组患者年龄、CCS、血肌酐(Scr)及氨基末端脑钠肽前体(NTＧproBNP)均显著高于预后良好组(P＜０．０５),无MACE生存时间及左心室射血分数(LVEF)显著低于预后良好组(P＜０．０５);CCS与年龄(r＝０．５１８,P＜０．０５)及Scr(r＝０．４０７,P＜０．０５)呈正相关,而与LVEF(r＝－０．２１５,P＜０．０５)呈负相关;受试者工作特征(ROC)曲线评估CCS预测MACE的曲线下面积(AUC)(９５％CI)为０．８４(０．７６~０．９２);CCS、LVEF及NTＧproBNP与患者预后不良相关,其优势比(OR)(９５％CI)分别为１．４６(０．６１~３．４９)、１．０１(０．９８~１．０５)及１．２４(１．０３~１．８２).【结论】CCS是接受介入治疗CAD患者近期预后不佳的独立危险因素,同时是潜在评估MACE的临床指标.[关键词]冠心病;经皮冠状动脉介入治疗;冠状动脉疾病;预后TheCorrelationbetweenCoronaryArteryCalciumScoreandShortＧTermPrognosisafterCoronaryArteryDiseaseInterventionalSurgeryZHANGHongwei,LIXinguo(DepartmentofGeriatricCardiovascularMedical,NorthCampus,Xi＇anInternationalMedicalCenter/Yan＇anUniversitySchoolofMedicine,Xi＇anShaanxi７１０１１９)[Abstract]【Objective】ToexplorethecorrelationbetweenCoronaryArteryCalciumScore(CCS)andtheshortＧtermprognosisofpatientswithCoronaryArteryDisease(CAD)afterinterventionalsurgery．【Methods】Atotalof１２０patientswhounderwentcoronaryarteryinterventionaltreatmentandcoronaryarteryCTangiography(CTA)wereincludedinthestudy．CCSwascalculatedforeachpatient．Patientswerefollowedupfor６monthsoutsidethehospitaltorecordtheocＧcurrenceofmajoradversecardiacevents(MACE)andthesurvivaltimewithoutevents．Basedonthose...
