论著盘龙七片联合萘丁美酮治疗腰椎间盘突出症对患者疼痛及血清相关指标的影响刘吉(安康市人民医院疼痛科,陕西安康７２５０００)[摘要]【目的】探讨盘龙七片联合萘丁美酮治疗腰椎间盘突出症对患者疼痛症状及血清相关指标的影响.【方法】６０例腰椎间盘突出症患者,随机分为观察组和对照组,每组３０例,对照组给予常规用药＋萘丁美酮治疗,观察组在对照组基础上给予盘龙七片治疗,比较两组疼痛改善情况、血清炎症指标、腰椎功能指标、临床疗效及不良反应发生情况.【结果】观察组治疗６周、治疗９周、治疗１２周后视觉模拟评分(VAS)均低于对照组;观察组治疗后血清肿瘤坏死因子Ｇα(TNFＧα)、白介素Ｇ１７(ILＧ１７)、白介素Ｇ１β(ILＧ１β)水平均低于对照组(P＜０．０５);观察组治疗３周、６周、９周、１２周后功能障碍指数(ODI)均低于对照组(P＜０．０５);观察组总有效率(８０．００％)高于对照组(５３．３３％)(P＜０．０５);两组不良反应发生率比较,差异无统计学意义(P＞０．０５).【结论】盘龙七片联合萘丁美酮治疗腰椎间盘突出症患者,可明显减轻疼痛症状,降低血清炎症水平,改善腰椎功能,临床效果显著且用药安全性高.[关键词]椎间盘移位/中西医结合疗法;腰椎;萘丁美酮/治疗应用;疼痛,手术后EffectofPanlongqiTabletsCombinedwithNabumetoneonPainandSerumＧRelatedIndicatorsinPatientswithLumbarDiscHerniationLIUJi(DepartmentofPainManagement,AnkangCityPeople＇sHospital,AnkangShaanxi７２５０００)[Abstract]【Objective】ToexploretheeffectofPanlongqitabletscombinedwithnabumetoneonpainsymptomsandserumＧrelatedindicatorsinpatientswithlumbardischerniation．【Methods】Atotalof６０patientswithlumbardischerniationwererandomlydividedintoanobservationgroupandacontrolgroup,eachwith３０patients．Thecontrolgroupreceivedconventionalmedication＋nabumetonetreatment,whiletheobservationgroupreceivedPanlongqitabＧletsontopofthecontrolgroup＇streatment．Thepainrelief,seruminflammatoryindicators,lumbarspinefunctioninＧdicators,clinicalefficacy,andincidenceofadversereactionswerecomparedinbothgroups．【Results】After６,９,and１２weeksoftreatment,thevisualanalogscale(VAS)scoresintheobservationgroupwerelowerthanthoseinthecontrolgroup．Aftertreatment,serumtumornecrosisfactorＧalpha(TNFＧ...
