论著腹腔镜下卵巢囊肿剔除术对患者卵巢功能、炎症因子及T淋巴细胞亚群水平的影响王敏李国玉王兰(安顺市妇幼保健院妇科,贵州安顺５６１０００)[摘要]【目的】探讨腹腔镜下卵巢囊肿剔除术对患者卵巢功能、炎症因子及T淋巴细胞亚群水平的影响.【方法】选取２０１９年１月至２０２３年１月本院妇科收治的７６例卵巢囊肿患者,根据手术方法不同分为对照组和观察组,每组３８例.对照组行开腹卵巢囊肿剔除术治疗,观察组行腹腔镜下卵巢囊肿剔除术治疗,比较两组手术前后卵巢功能[雌二醇(E２)、促卵泡激素(FSH)、黄体生成素(LH)]、炎症因子[白细胞介素Ｇ６(ILＧ６)、肿瘤坏死因子Ｇα(TNFＧα)、C反应蛋白(CRP)]及T淋巴细胞亚群水平(CD３＋、CD４＋及CD４＋/CD８＋).【结果】两组术后３个月FSH、LH均升高,但观察组低于对照组(P＜０．０５);两组术后３个月E２均降低,但观察组高于对照组(P＜０．０５).观察组患者术后ILＧ６、TNFＧα、CRP水平低于对照组,差异有统计学意义(P＜０．０５).两组患者术前CD４＋、CD４＋/CD８＋比较,差异无统计学意义(P＞０．０５);术后１d,两组患者血清CD３＋、CD４＋、CD４＋/CD８＋均较术前明显降低,但观察组高于对照组,差异均有统计学意义(P＜０．０５);观察组患者术后３d血清CD３＋、CD４＋、CD４＋/CD８＋恢复至术前水平.【结论】腹腔镜下卵巢囊肿剔除术可有效促进患者卵巢功能恢复,并减轻机体炎症反应,提高T淋巴细胞亚群水平,减轻对机体细胞免疫功能的抑制,有利于患者术后康复.[关键词]卵巢囊肿/外科学;腹腔镜检查;卵巢功能试验;T淋巴细胞亚群TheEffectsofLaparoscopicOvarianCystectomyonOvarianFunction,InflammatoryFactorsandTLymphocyteSubsetsWANGMin,LIGuoyu,WANGLan(DepartmentofGynecology,AnshunMaternalandChildHealthHospital,AnshunGuizhou５６１０００)[Abstract]【Objective】Toexploretheeffectsoflaparoscopicovariancystectomyonovarianfunction,inＧflammatoryfactors,andTlymphocytesubsetsinpatients．【Methods】Atotalof７６patientswithovariancystsadmittedtothegynecologydepartmentofourhospitalfromJanuary２０１９toJanuary２０２３wereselectedanddiＧvidedintoacontrolgroupandanobservationgroupbasedondifferentsurgicalmethods,with３８casesineachgroup．Thecontrolgroupunderwentopenovariancystectomy,whiletheobservationgroupunderwentlaparoＧscopicovariancystectomy．Ovarianfun...
