论著桂枝甘草汤联合常规西药治疗慢性心力衰竭患者的临床疗效赵丽晨(天津市公安医院,天津３０００４０)[摘要]【目的】探讨桂枝甘草汤联合常规西药治疗慢性心力衰竭(简称心衰)患者的临床疗效.【方法】选择本院收治的１０２例慢性心衰患者,根据随机数字表法将其分为观察组和对照组,每组５１例.对照组采用常规西药治疗,观察组在对照组基础上加用桂枝甘草汤.治疗１个月后,比较两组临床疗效、不良反应发生情况,以及治疗前后实验室指标[高敏C反应蛋白(hsＧCRP)、氨基末端B型脑钠肽前体(NTＧproBNP)、红细胞分布宽度(RDW)]、中医证候评分、心功能指标[左心室舒张末期内经(LVEDD)、左心室收缩末期内径(LVESD)、左室射血分数(LVEF)].【结果】观察组患者总有效率明显高于对照组,差异有统计学意义(P＜０．０５).治疗后,两组气短心悸、咳嗽咯痰、少气懒言评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P＜０．０５);观察组患者NTＧproBNP、hsＧCRP、RDW水平明显低于治疗前及对照组治疗后(P＜０．０５);两组患者LVEDD、LVESD低于治疗前,LVEF高于治疗前,观察组LVEDD、LVESD低于对照组,LVEF高于对照组,差异有统计学意义(P＜０．０５).两组患者不良反应总发生率比较,差异无统计学意义(P＞０．０５).【结论】在常规西医治疗的基础上应用桂枝甘草汤治疗慢性心衰,可提高临床治疗效果,改善心功能,安全性高,值得临床推广应用.[关键词]心力衰竭/中西医结合疗法;慢性病;治疗结果ClinicalEfficacyofGuizhiGancaoDecoctionCombinedwithConventionalWesternMedicineintheTreatmentofPatientswithChronicHeartFailureZHAOLichen(TheTianjinPublicSecurityHospital,Tianjin３０００４０)[Abstract]【Objective】ToinvestigatetheclinicalefficacyofGuizhiGancaoDecoctionCombinedwithconventionalwesternmedicineinthetreatmentofpatientswithchronicheartfailure．【Methods】Atotalof１０２patientswithchronicheartfailurewereselectedanddividedintoobservationgroupandcontrolgroupaccordingtotherandomnumbertablemethod,with５１casesineachgroup．Thecontrolgroupwastreatedwithconventionalwesternmedicine,andtheobservaＧtiongroupwastreatedwithGuizhiGancaoDecoctiononthebasisofthecontrolgroup．Afteronemonthoftreatment,theclinicalefficacy,theoccurrenceofadversereactions,andthelaboratoryindexes[highＧsensitivityCＧreactiveprotein(hsＧCR...
