著·白:410.JiangsuJPrevMed,Jul.,,2023,Vol.34,No.4江苏预防医学2023年7月第34卷第4期江苏省恙虫病高发地区农民血清学调查及感染危险因素分析李志锋，梁舒怡，田华，秦圆方，胡建利，鲍侣俊江苏省疾病预防控制中心，江苏南京210009摘要：目的了解江苏省恙虫病高发地区农民感染情况及相关危险因素，为恙虫病防控提供流行病学依据。方法在江苏省南部和北部6个高发县/区随机抽取2537名农民为调查对象，应用免疫层析法（胶体金）检测血清样本中虫病东方体IgG和IgM抗体，阳性样本采用间接免疫荧光法检测相应的IgM和IgG抗体滴度。结果2537名调查对象IgM抗体均为阴性，IgG抗体血清阳性率为1.58%（男性0.86%，女性2.26%）。多因素分析显示，女性（0R=3.562,P=0.008）、年龄>60岁（参照15~30岁：0R=7.981,P=0.003）、放牧（OR=16.981,P<0.001）、割草（OR=16.152,P<0.001）、养羊（OR=11.212,P=0.005）、钓鱼（0R=5.850,P=0.005）、干农活的时间≥3h/d（0R=4.263,P=0.002）是恙虫病东方体感染的危险因素。结论江苏省恙虫病高发地区农民室外劳作有较高的暴露风险，应加强个人防护。关键词：恙虫病东方体；血清学；危险因素；江苏；农民中图分类号：R513.2文献标识码：A文章编号：1006-9070(2023)04-0410-03SeroprevalenceandriskfactorsofscrubtyphusamongfarmersinhighlyprevalentregionsofJiangsuProvinceLIZhi-Feng,LIANGShu-Yi,TIANHua,QINYuan-Fang,HUJian-Li,BAOChang-JunJiangsuProvincialCenterforDiseaseControlandPrevention,Nanjing,Jiangsu210009,ChinaAbstract:ObjectiveToinvestigatetheseroprevalenceandriskfactorsofscrubtyphusamongfarmersinhighlyprevalentregionsofJiangsuProvince,soastoprovideepidemiologicalevidenceforscrubtyphuscontrol.MethodsAtotalof2537farmerswererandomlysampledfrom6counties(districts)insouthernandnorthernJiangsuProvince.SerumIgGandIgMantibodiesagainstOrientiatsutsugamushiweredetectedusingacolloidalgoldimmunochromatographicassay,andanti-IgMandIgGantibodytitersweredetectedamongpositiveserumsamplesusingindirectimmunofluorescenceassay.ResultsAllparticipantsweretestednegativeforlgMantibodyagainst0.tsutsugamushi,andtheseroprevalenceofanti-0.tsutsugamushiIgGantibodywas1.58%(0.86%inmenand2.26%inwomen).Multivariatelogisticregressionanalysisidentifiedwomen[oddsratio...
