医学研究杂志2024年2月第53卷第2期·论着·卵巢多囊样改变合并不孕症患者AMH水平对卵母细胞发育潜能的影响李雪敏杨贵芳田珏郭瑞霞杨晓丽摘要目的探讨卵巢多囊样改变（polycysticovarianmorphology,PCOM）合并不孕症患者体外受精－胚胎移植中抗苗勒管激素（anti-Millerianhormone,AMH)水平对卵母细胞发育潜能的影响。方法选取符合纳人与排除标准的不孕症患者480例（对照组160例、PCOM组104例、PCOS组216例），比较不同组间AMH水平。PCOM及PCOS人群均按血清AMH水平（≤4.7ng/ml为正常值，>4.7ng/ml为高值）分为正常AMH组和高AMH组，分析PCOM及PCOS人群不同AMH水平组间的卵母细胞指标差异及其相关性。结果PCOS人群血清基础雄激素高于PCOM人群(P<0.01);血清AMH水平比较：对照组
O.05）。结论PCOM合并不孕症人群血清AMH水平较对照组升高但低于PCOS人群,高AMH水平的PCOM患者可获得质量较好的卵母细胞及更多的胚胎，增加临床中反复移植失败患者移植次数，提高临床妊娠率。关键词抗苗勒管激素体外受精－胚胎移植卵巢多囊样改变多囊卵巢综合征卵母细胞发育潜能中图分类号R71EffectofAnti-MullerianHormoneLevelontheDevelopmentalPotentialofOocytesinPatientswithPolycysticOvarianMorphologycom-binedwithInfertility.LIXuemin,YANGGuifang,TIANJue,etal.TheNinthClinicalMedicalCollegeofShanxiMedicalUniversity(TaiyuanCentralHospital),Shanxi030009,ChinaAbstractObjectiveToinvestigatetheeffectofanti-Mullerianhormone(AMH)levelsonthedevelopmentpotentialofoocytesinpatientswithpolycysticovarianmorphology(PCOM)complicatedwithinfertilityduringinvitrofertilization-embryotransfer.MethodsAtotalof480infertilepatientswhomettheinclusionandexclusioncriteriawereselected(160casesincontrolgroup,104casesinPCOMgroupand216casesinPCOSgroup),AMHlevelswerecomparedamongdi...
