论著急性心肌梗死冠状动脉微循环阻力指数的影响因素分析肖红芳姜艳艳∗(北京中医药大学孙思邈医院,陕西铜川７２７０００)[摘要]【目的】探讨急性心肌梗死(AMI)冠脉微循环阻力指数(IMR)的影响因素.【方法】选择２０１９年３月至２０２１年６月本院收治的６７例AMI患者,采用二分类法以IMR正常值２５为界值将患者分为正常IMR组(对照组,n＝２９,IMR≤２５)和观察组(n＝３８,IMR＞２５).比较两组患者临床资料,采用Pearson相关性分析IMR与各临床因素之间的关系,应用多因素Logistic回归曲线分析各临床指标与高水平IMR的相关性.【结果】观察组患者年龄、低密度脂蛋白胆固醇(LDLＧC)、心肌肌钙蛋白I(cTnI)及肌酸激酶同工酶(CKＧMB)、病变血管长度高于对照组,术后TIMI血流分级、左室射血分数(LVEF)低于对照组,差异有统计学意义(P＜０．０５).Pearson相关性分析显示,IMR与cTnI、年龄呈正相关(P＜０．０５),与术后TIMI血流分级、LVEF呈负相关(P＜０．０５);IMR与病变血管长度、CKＧMB无显著相关性(P＞０．０５).多因素Logistic回归分析结果显示,cTnI、术后TIMI血流分级、LVEF是IMR的影响因素,其优势比(OR)(９５％CI)分别为２．０１(１．０２~３．８８)、１．０３(０．８７~１．９５)、０．３６(０．０７~０．９３),差异均有统计学意义(P＜０．０５).【结论】cTnI、术后TIMI血流分级、LVEF是AMI患者IMR的影响因素.[关键词]心肌梗死;急性病;冠状动脉循环;影响因素分析AnalysisofFactorsInfluencingCoronaryMicrocirculatoryResistanceIndexinAcuteMyocardialInfarctionXIAOHongfang,JIANGYanyan(SunSimiaoHospital,BeijingUniversityofChineseMedicine,TongchuanShaanxi７２７０００)[Abstract]【Objective】Toexploretheinfluencingfactorsofcoronarymicrocirculationresistanceindex(IMR)inacutemyocardialinfarction(AMI)．【Methods】Atotalof６７AMIpatientsadmittedtoourhospitalfromMarch２０１９toJune２０２１wereselectedinthestudyandtheyweredividedintoanormalIMRgroup(thecontrolgroup,n＝２９,IMR≤２５)andanobservationgroup(n＝３８,IMR＞２５)usingabinaryclassificationmethodwithanormalIMRvalueof２５asthecutoff．Clinicaldataofthetwogroupsofpatientswerecompared,usingPearsoncorrelationanalysistoanalyzetherelationshipbetweenIMRandvariousclinicalfactorsandmultivariatelogisticregressioncurvetoanalyzethecorrelationbetwe...
