123AnIntroductiontoClinicalResearchBryanKestenbaumSecondEditionEpidemiologyandBiostatisticsEpidemiologyandBiostatisticsBryanKestenbaumEpidemiologyandBiostatisticsAnIntroductiontoClinicalResearchSecondEditionEditorsNoelS.Weiss,MDPhDDepartmentofEpidemiologyUniversityofWashingtonSeattle,WAUSAAbigailShoben,PhDBiostatistics,CollegeofPublicHealthTheOhioStateUniversityColumbus,OHUSAISBN978-3-319-96642-7ISBN978-3-319-96644-1(eBook)https://doi.org/10.1007/978-3-319-96644-1LibraryofCongressControlNumber:2018955511©SpringerNatureSwitzerlandAG2009,2019Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeorpartofthematerialisconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcasting,reproductiononmicrofilmsorinanyotherphysicalway,andtransmissionorinformationstorageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdeveloped.Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse.Thepublisher,theauthors,andtheeditorsaresafetoassumethattheadviceandinformationinthisbookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsortheeditorsgiveawarranty,expressorimplied,withrespecttothematerialcontainedhereinorforanyerrorsoromissionsthatmayhavebeenmade.Thepublisherremainsneutralwithregardtojurisdictionalclaimsinpublishedmapsandinstitutionalaffiliations.ThisSpringerimprintispublishedbytheregisteredcompanySpringerNatureSwitzerlandAGTheregisteredcompanyaddressis:Gewerbestrasse11,6330Cham,SwitzerlandBryanKestenbaum,MD,MSDivisionofNephrologyDepartmentofMedicineUniversityofWashingtonSeattle,WAUSAvPrefaceThistextbookwasoriginallycreatedfromadisparatecollectionofmaterialsusedtoteachEpidemiologyandBiostatisticstosecond-yearmedicalstudentsattheUniversityofWashington...
