ClinicalTrialsinPsychopharmacologySECONDEDITIONClinicalTrialsinPsychopharmacology:ABetterBrain,SecondEditionEditedbyM.HertzmanandL.Adler©2010JohnWiley&Sons,Ltd.ISBN:978-0-470-74076-7ClinicalTrialsinPsychopharmacologyABetterBrainSECONDEDITIONEditorsMarcHertzmanResearchPsychiatristandformerlyProfessorofPsychiatry,GeorgeWashingtonUniversity,USALawrenceAdlerUniversityofMarylandSchoolofMedicine,USAThiseditionfirstpublished2010©2010JohnWiley&Sons,LtdWiley-BlackwellisanimprintofJohnWiley&Sons,formedbythemergerofWiley’sglobalScientific,TechnicalandMedicalbusinesswithBlackwellPublishing.Registeredoffice:JohnWiley&SonsLtd,TheAtrium,SouthernGate,Chichester,WestSussex,PO198SQ,UKOtherEditorialOffices:9600GarsingtonRoad,Oxford,OX42DQ,UK111RiverStreet,Hoboken,NJ07030-5774,USAFordetailsofourglobaleditorialoffices,forcustomerservicesandforinformationabouthowtoapplyforpermissiontoreusethecopyrightmaterialinthisbookpleaseseeourwebsiteatwww.wiley.com/wiley-blackwell.TherightoftheauthortobeidentifiedastheauthorofthisworkhasbeenassertedinaccordancewiththeCopyright,DesignsandPatentsAct1988.Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystem,ortransmitted,inanyformorbyanymeans,electronic,mechanical,photocopying,recordingorotherwise,exceptaspermittedbytheUKCopyright,DesignsandPatentsAct1988,withoutthepriorpermissionofthepublisher.Wileyalsopublishesitsbooksinavarietyofelectronicformats.Somecontentthatappearsinprintmaynotbeavailableinelectronicbooks.Designationsusedbycompaniestodistinguishtheirproductsareoftenclaimedastrademarks.Allbrandnamesandproductnamesusedinthisbookaretradenames,servicemarks,trademarksorregisteredtrademarksoftheirrespectiveowners.Thepublisherisnotassociatedwithanyproductorvendormentionedinthisbook.Thispublicationisdesignedtoprovideaccurateandauthoritativeinformationinregardtothesubjectmattercovered.Itissoldontheunderstandingthatthepublisherisnotengagedinrenderingprofessionalservices.Ifprofessionaladviceorotherexpertassistanceisrequired...