MethodsandApplicationsofStatisticsinClinicalTrialsVolume2WILEYSERIESINMETHODSANDAPPLICATIONSOFSTATISTICSAdvisoryEditorN.BalakrishnanMcMasterUniversity,CanadaTheWileySeriesinMethodsandApplicationsofStatisticsisauniquegroupingofresearchthatfeaturesclassiccontributionsfromWiley'sEncyclopediaofStatisticalSciences,SecondEdition(ESS,2e)alongsidenewlywrittenarticlesthatexplorevariousproblemsofinterestandtheirintrinsicconnectiontostatistics.Thegoalofthiscollectionistoencompassanencyclopedicscopeofcoveragewithinindividualbooksthatunifythemostimportantandinterestingapplicationsofstatisticswithinaspecificfieldofstudy.EachbookintheseriessuccessfullyupholdsthegoalsofESS,2ebycombiningestablishedliteratureandnewlydevelopedcontributionswrittenbyleadingacademics,researchers,andpractitionersinacomprehensiveandaccessibleformat.Theresultisasuccinctreferencethatunveilsmodern,cutting-edgeapproachestoacquiring,analyzing,andpresentingdataacrossdiversesubjectareas.WILEYSERIESINMETHODSANDAPPLICATIONSOFSTATISTICSBalakrishnan•MethodsandApplicationsofStatisticsintheLifeandHealthSciencesBalakrishnan•MethodsandApplicationsofStatisticsinBusiness,Finance,andManagementScienceBalakrishnan•MethodsandApplicationsofStatisticsinEngineering,QualityControl,andthePhysicalSciencesBalakrishnan•MethodsandApplicationsofStatisticsintheSocialandBehavioralSciencesBalakrishnan•MethodsandApplicationsofStatisticsintheAtmosphericandEarthSciencesBalakrishnan•MethodsandApplicationsofStatisticsinClinicalTrials,Volume1:Concepts,Principles,Trials,andDesignsBalakrishnan•MethodsandApplicationsofStatisticsinClinicalTrials,Volume2:Planning,Analysis,andInferentialMethodsMethodsandApplicationsofStatisticsinClinicalTrialsVolume2Planning,Analysis,andInferentialMethodsEditedbyN.BalakrishnanMcMasterUniversityDepartmentofMathematicsandStatisticsHamilton,Ontario,CanadaWILEYCopyright©2014byJohnWiley&Sons,Inc.Allrightsreserved.PublishedbyJohnWiley&Sons,Inc.,Hoboken,NewJersey.Allrightsreserved.PublishedsimultaneouslyinCanada.N...
