SubmitManuscriptsOnlineathttps://mc.manuscriptcentral.com/ebmExperimentalBiologyandMedicineMandatorySubmissionFormRev.1/1/2015ManuscriptNumber:Title:ASignatureBelowCertifiesCompliancewiththeFollowingStatementsCopyrightTransfer.Inconsiderationofacceptanceoftheaboveworkforpublication,IdoherebyassignandtransfertotheSocietyforExperimentalBiologyandMedicine(SEBM)allrights,title,andinterestinandtothecopyrightintheabove-titledwork.Thisincludespreliminarydisplay/postingoftheabstractoftheacceptedarticleinelectronicformbeforepublication.TheJournalgrantstheAuthorpermissiontoprovideacopyoftheacceptedmanuscripttoNIHuponacceptanceforJournalpublication,withpublicreleaseinPubMedCentraltwelvemonthsafterfinalprintpublicationbytheJournal.Ifanychangesinauthorship(order,deletions,oradditions)occurafterthemanuscriptissubmitted,agreementbyallauthorsforsuchchangesmustbeonfilewithSEBM.Anauthor’snamemayonlyberemovedathis/herownrequest.Forcommercialcompanies,authorizedagents’signaturesareallowedforcopyrighttransfer,butthecorrespondingauthormustsignforauthorshipresponsibilitiesasstatedbelow.MaterialpreparedbyemployeesfortheUSGovernmentinthecourseoftheirofficialdutiescannotbecopyrighted.Nevertheless,authorsmustsigntheformtoindicateacceptanceofalltermsotherthancopyrighttransfer.AuthorshipResponsibilities.Iattestthat:1)themanuscriptisnotcurrentlyunderconsideration,inpress,orpublishedelsewhere,andtheresearchreportedwillnotbesubmittedforpublicationelsewhereuntilafinaldecisionhasbeenmadeastoitsacceptabilitybythejournal.Ifevidenceofdualsubmissionisfound,themanuscriptwillberejectedor,ifpublished,retracted.(postingofsubmittedmaterialonawebsitemaybeconsideredpriortopublication-notethisinyourcoverletter):2)themanuscriptistruthfuloriginalworkwithoutfabrication,fraud,orplagiarism;3)Ihavemadesignificantscientificcontributionstothestudy,amthoroughlyfamiliarwiththeprimarydata,havereviewedthemanuscript,andmyspecificcontribution(s)is(are)indicatedintheStatementofAuthorContributions;and4)Ihavereadthecomplet...