InvestigativeElectrocardiographyinEpidemiologicalStudiesandClinicalTrialsPenttiRautaharjuandFaridaRautaharjuInvestigativeElectrocardiographyinEpidemiologicalStudiesandClinicalTrialsPenttiRautaharju,MD,PhDFaridaRautaharju,PhDWakeForestUniversitySchoolofMedicineCovanceCardiacSafetyServicesWinston-Salem,NorthCarolinaReno,NevadaUSAUSABritishLibraryCataloguinginPublicationDataRautaharju,P.(Pentti)Investigativeelectrocardiographyinepidemiologicalstudiesandclinicaltrials1.Electrocardiography2.Heart–Diseases–Epidemiology3.ClinicaltrialsI.TitleII.Rautaharji,Farida616.1'207547ISBN-13:9781846284656ISBN-10:1846284651LibraryofCongressControlNumber:2006926452ISBN-10:1-84628-465-1eISBN1-84628-481-3Printedonacid-freepaperISBN-13:978-1-84628-465-6©Springer-VerlagLondonLimited2007Apartfromanyfairdealingforthepurposesofresearchorprivatestudy,orcriticismorreview,aspermittedundertheCopyright,DesignsandPatentsAct1988,thispublicationmayonlyberepro-duced,storedortransmitted,inanyformorbyanymeans,withthepriorpermissioninwritingofthepublishers,orinthecaseofreprographicreproductioninaccordancewiththetermsoflicencesissuedbytheCopyrightLicensingAgency.Enquiriesconcerningreproductionoutsidethosetermsshouldbesenttothepublishers.Theuseofregisterednames,trademarks,etc.inthispublicationdoesnotimply,evenintheabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantlawsandregulationsandthereforefreeforgeneraluse.Productliability:Thepublishercangivenoguaranteeforinformationaboutdrugdosageandappli-cationthereofcontainedinthisbook.Ineveryindividualcasetherespectiveusermustcheckitsaccuracybyconsultingotherpharmaceuticalliterature.987654321SpringerScience+BusinessMediaspringer.comTO:Anu,Kristina,MiaSatuSherene,RizaviiPrefaceThisbookoninvestigativeelectrocardiographyisaddressedtoinvestigatorswhoareusingelectrocardiologyasaresearchtoolinepidemiologicalorclinicalresearchorininvestigationsonpossibleadverseresponsesofnewpharmacologicalagents.TheprimaryemphasisofthebookisonprognosticimplicationsofE...
