·171·中国现代药物应用2024年3月第18卷第6期ChinJModDrugAppl,Mar2024,Vol.18,No.6厚朴排气合剂治疗骨折围手术期便秘的研究进展何福飞叶友友林焱斌【摘要】便秘是骨折围手术期的常见并发症,是长期困扰骨科医生的临床问题。相关研究表明骨折围手术期便秘如未及时治疗,可导致诸多并发症,并且延长住院时间,增加医疗支出。相对于西医而言,中医在治疗骨折围手术期便秘方面具有独特优势,中医提倡辨证论治,注重对患者临床症状以及生活质量的改善,为适应临床需要,在中医思想的指导下,厚朴排气合剂便应运而生。文章就骨折患者围手术期便秘的病因病机和近年来厚朴排气合剂的临床应用予以综述。【关键词】厚朴排气合剂;骨折;围手术期;便秘DOI:10.14164/j.cnki.cn11-5581/r.2024.06.045ResearchprogressofHoupuPaiqimixtureintreatingconstipationduringperioperativeperiodoffractureHEFu-fei,YEYou-you,LINYan-bin.FujianUniversityofTraditionalChineseMedicine,Fuzhou350000,China【Abstract】Constipationisacommoncomplicationinperioperativeperiodoffracture,anditisaclinicalproblemthattroublesorthopedicdoctorsforalongtime.Relatedstudieshaveshownthatperioperativeconstipation,ifnottreatedintime,canleadtomanycomplications,prolonghospitalstayandincreasemedicalexpenses.ComparedwithWesternmedicine,Chinesemedicinehasauniqueadvantageinthetreatmentofconstipationintheperioperativeperiodoffracture.Chinesemedicineadvocatesthetreatmentofsyndromedifferentiationandpaysattentiontotheimprovementofclinicalsymptomsandqualityoflifeofpatients.Inordertomeettheclinicalneeds,undertheguidanceofChinesemedicine,HoupuPaiqimixturecameintobeing.ThisarticlereviewstheetiologyandpathogenesisofperioperativeconstipationinfracturepatientsandtheclinicalapplicationofHoupuPaiqimixtureinrecentyears.【Keywords】HoupuPaiqimixture;Fracture;Perioperativeperiod;Constipation便秘通常指排便形状改变、排便干燥、次数减少、且排便不畅。骨折患者因创伤刺激、手术麻醉、术后长期卧床、止痛药物的使用、疾病的心理影响等因素的影响,使得骨折围手术期便秘的发生率高达50%~70%[1]。相关研究表明,便秘影响骨折患者的病情恢复、对患者的生活质量有不利影响[2]。大量研究表明,中药厚朴排气合剂可有效促进肠道排便、排气,...