·96·中国现代药物应用2024年2月第18卷第4期ChinJModDrugAppl,Feb2024,Vol.18,No.4克霉唑阴道片治疗霉菌性阴道炎的临床疗效观察张歌【摘要】目的研究克霉唑阴道片治疗霉菌性阴道炎的疗效。方法128例霉菌性阴道炎患者,根据随机数字编号方法分为观察组(63例)和对照组(65例)。对照组患者使用硝酸咪康唑栓(商品名：达克宁)治疗,观察组应用克霉唑阴道片治疗。比较两组临床疗效和用药不良反应发生率。结果观察组治疗总有效率95.24%(60/63)高于对照组的84.62%(55/65),差异有统计学意义(P<0.05)。观察组治疗后的不良反应发生率4.76%(3/63)低于对照组的20.00%(13/65),差异有统计学意义(P<0.05)。结论临床上对霉菌性阴道炎患者通过克霉唑阴道片进行治疗的效果比达克宁更好,安全性更高,直接推荐。【关键词】克霉唑阴道片；霉菌性阴道炎；硝酸咪康唑栓；临床疗效；不良反应DOI：10.14164/j.cnki.cn11-5581/r.2024.04.026ClinicalefficacyofclotrimazolevaginaltabletinthetreatmentofmycoticvaginitisZHANGGe.ChaoyangSecondHospital,Chaoyang122000,China【Abstract】ObjectiveTostudytheefficacyofclotrimazolevaginaltabletinthetreatmentofmycoticvaginitis.Methods128patientswithmycoticvaginitisweredividedintoanobservationgroup(63cases)andacontrolgroup(65cases)accordingtorandomnumbernumberingmethod.Thecontrolgroupwastreatedwithmiconazolenitratesuppositories(tradename:Gyno-Daktarin),andtheobservationgroupwastreatedwithclotrimazolevaginaltablet.Theclinicalefficacyandincidenceofadversedrugreactionswerecomparedbetweenthetwogroups.ResultsThetotaleffectiverateoftheobservationgroupwas95.24%(60/63),whichwashigherthan84.62%(55/65)ofthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05).Theincidenceofadversereactionsaftertreatmentintheobservationgroupwas4.76%(3/63),whichwaslowerthan20.00%(13/65)inthecontrolgroup,andthedifferencewasstatisticallysignificant(P<0.05).ConclusionInclinicalpractice,theuseofclotrimazolevaginaltabletsforthetreatmentofmycoticvaginitisismoreeffectiveandsaferthandactylinesuppositories.Itisrecommended.【Keywords】Clotrimazolevaginaltablet;Mycoticvaginitis;Miconazolenitratesuppositories;Clinicalefficacy;Adversereactions最近这些年因为思...
