·75·中国现代药物应用2024年2月第18卷第4期ChinJModDrugAppl,Feb2024,Vol.18,No.4倍他乐克联合苯磺酸左旋氨氯地平治疗原发性高血压的有效性分析赵广华【摘要】目的探究原发性高血压患者行酒石酸美托洛尔片(商品名：倍他乐克)、苯磺酸左旋氨氯地平联合治疗的效果。方法30例原发性高血压1、2级患者,随机分为实验组(18例)与对照组(12例)。实验组应用苯磺酸左旋氨氯地平+倍他乐克治疗,对照组应用苯磺酸左旋氨氯地平治疗。比较两组临床疗效、不良反应发生率及治疗前后血压、心率、动脉硬化指数。结果实验组总有效率94.44%高于对照组的66.67%(P<0.05)。治疗后,实验组收缩压(122.15±4.46)mmHg(1mmHg=0.133kPa)、舒张压(88.16±4.43)mmHg、心率(76.75±13.04)次/min均低于对照组的(140.51±7.34)mmHg、(95.54±6.67)mmHg、(89.74±9.26)次/min(P<0.05)。治疗后,实验组动脉硬化指数(3.54±0.17)低于对照组的(5.11±1.01)(P<0.05)。实验组不良反应发生率5.56%低于对照组的41.67%(P<0.05)。结论联用倍他乐克、苯磺酸左旋氨氯地平治疗原发性高血压患者的效果确切,可有效调节血压水平和动脉硬化指数,不良反应少,推广可行性显著。【关键词】酒石酸美托洛尔片；苯磺酸左旋氨氯地平；原发性高血压；有效性DOI：10.14164/j.cnki.cn11-5581/r.2024.04.020AnalysisofeffectivenessofBetaloccombinedwithlevamlodipinebesylateinthetreatmentofessentialhypertensionZHAOGuang-hua.CommunityHealthServiceCenter,QingmingqiaoStreet,LiangxiDistrict,Wuxi214000,China【Abstract】ObjectiveToexploretheeffectofmetoprololtartratetablets(tradename:Betaloc)combinedwithlevamlodipinebesylateinthetreatmentofessentialhypertension.Methods30patientswithgrade1or2essentialhypertensionwererandomlydividedintoanexperimentalgroup(18cases)andacontrolgroup(12cases).TheexperimentalgroupwastreatedwithlevamlodipinebesylateandBetaloc,andthecontrolgroupwastreatedwithlevamlodipinebesylate.Theclinicalefficacy,incidenceofadversereactions,bloodpressure,heartrate,arteriosclerosisindexbeforeandaftertreatmentwerecomparedbetweenthetwogroups.ResultsThetotaleffectiverateoftheexperimentalgroupwas94.44%,whichwashigherthan66.67%ofthecontrolgroup(P<0.05).Aftertreatment,theexperimentalgrouphadsystolicbloodpressureof(122.15±4.46)mmHg(1...
