·79CHINESEJOURNALOFCTANDMRI,FEB.2023,Vol.21,No.02TotalNo.160【第一作者】古力斯坦·卡迪尔，女，主治医师，主要研究方向：心血管超声及经食道超声心动图的诊断。E-mail：yevte16@163.com【通讯作者】吕娟，女，副主任医师，主要研究方向：超声造影。E-mail：lj1984l@163.com论著SerumESR,IL-6,MMP-9LevelsinPatientswithTakayasuArteritisandTheirCorrelationwithCEUS-RelatedParameters*GulistanKadir1,NafisaEli1,ZHOUMin1,MubarakBaihetyar2,LVJuan1,*.1.UltrasoundDepartmentofXinjiangUygurAutonomousRegionPeople'sHospital,Urumqi830001,Xinjiang,China2.ThePeople'sHospitalofXinjiangUygurAutonomousRegion,UndergoingClinicalExamination,Urumqi830001,Xinjiang,ChinaABSTRACTObjectiveTostudytherelationshipbetweenserumerythrocytesedimentationrate(ESR),interleukin-6(IL-6),matrixmetalloproteinase-9(MMP-9)levelsandcontrast-enhancedultrasound-relatedparametersinpatientswithTakayasuarteritis.Methods36patientswithTakayasuarteritis(TA)acceptedbyourhospitalfromJanuary2019toApril2022(TAgroup)wereincluded.AccordingtothecriteriaestablishedbytheNationalInstitutesofTechnology,theyweregroupedintoanactivegroupof26casesandaninactivegroupof10cases.Atotalof40healthysubjectsfromJanuary2019toApril2022wereselectedascontrolgroup.AllpatientswithTAunderwentcontrast-enhancedultrasonography.ThelevelsofserumESRandIL-6andMMP-9ineachgroupweredetectedandcompared.ThecorrelationbetweenserumESR,IL-6,MMP-9andCEUSparameterswasanalyzedbyPearsonmethod.ResultsThelevelsofserumESR,IL-6,MMP-9,andtimetopeak(TTP)inTAgroupwerehigherthanthoseincontrolgroup(P<0.05),theareaunderthecurve(AUC),ascendingbranchslope(A),peakvalueIntensity(PI)waslowerthanthoseincontrolgroup(P<0.05).Comparedwiththeinactivegroup,thelevelsofserumESR,IL-6,MMP-9,andTTPoftheactivegroupwerehigher(P<0.05),andtheAUC,A,andPIwerelower(P<0.05).Pearson'smethodanalysisshowedthatESR,IL-6,MMP-9werenegativelycorrelatedwithAUC,A,andPI(P<0.05),andpositivelycorrelatedwithTTP(P<0.05).ConclusionThelevelsofserumESR,IL-6andMMP-9inTApatientsaresignificantlyup-regulated,andCEUS-relatedparametershav...
