2022年11月第8卷第11期**论著论著**磁共振ADC值在乳腺良恶性病变鉴别诊断中的价值马洪舟马洪舟，刘伟娟刘伟娟菏泽市立医院放射科MRI室，山东菏泽274000摘要摘要目的评估磁共振表观弥散系数（apparentdiffusioncoefficient，ADC）值在鉴别乳腺良恶性病变中的作用，并确立最佳诊断阈值。方法回顾性分析菏泽市立医院自2018年1月—2022年3月期间行磁共振检查的乳腺良恶性病变102例，均经病理证实，均在常规序列基础上加扫描DWI序列，并自动重建ADC图。其中恶性组55例，良性组47例，每个病变均测量ADC值。分析两组间ADC值的差异，并做ROC曲线分析。结果恶性组ADC值均值为（0.99±0.25）×10−3mm2/s，良性组ADC值均值为（1.64±0.32）×10−3mm2/s，两组间差异有统计学意义（t=11.347，P<0.001）。ROC曲线分析显示将诊断阈值定为1.11×10−3mm2/s时，诊断的敏感性为90.9%，特异性为97.9%，诊断准确率为96.0%。结论磁共振ADC值在乳腺良恶性病变鉴别诊断中，敏感性和特异性高，具有较高的应用价值。关键词关键词磁共振；ADC值；乳腺良恶性病变中图分类号中图分类号R4文献标志码文献标志码Adoi10.11966/j.issn.2095-994X.2022.08.11.03TheValueofMagneticResonanceADCValuesintheDifferentialDiagnosisofBe⁃nignandMalignantBreastLesionsMAHongzhou,LIUWeijuanMRIRoom,DepartmentofRadiology,HezeMunicipalHospital,Heze,ShandongProvince,274000ChinaAbstractObjectiveToevaluatetheroleofMRIapparentdiffusioncoefficient(ADC)valuesinthedifferentialdiagnosisofbenignandmalig⁃nantbreastlesions,andtoestablishtheoptimaldiagnosticthreshold.MethodsRetrospectiveanalysisof102casesofbenignandmalignantbreastlesionsinHezeMunicipalHospitalwhounderwentMRIfromJanuary2018toMarch2022,allconfirmedbypathology,werescannedwithDWIsequencesontopofconventionalsequences,andADCmapswereautomaticallyreconstructed.Amongthem,55caseswereinthemalignantgroupand47casesinthebenigngroup,andADCvaluesweremeasuredforeachlesion.ThedifferencesinADCvaluesbetweenthetwogroupswereanalyzed,andROCcurveanalysiswasdone.ResultsThemeanADCvaluewas(0.99±0.25)×10-3mm2/sinthemalignantgroupand(1.64±0.32)×10-3mm2/sinthebenigngroup,thedifferencewasstatisticallysignificantbetweenthetwogroups(t=11.347,P<0.001).TheROCcurveanalysissho...
