1SCI写作高大上句型1000例—801‐900801、However,althoughitiswelldocumentedthat…,muchmorelimitedandcontroversialinformationexistsabouttheeffectsofXXXonthecardiacinterstitium;however,somereportssuggestthatthesedrugsinhibitinterstitialfibrosis，thisisnotconfirmedbyotherstudies.802、Inrecentexperimentsdesignedtoaddressthemechanismsunderlyingtheantihypertrophiceffectofpropranololinpressure‐overloadedrats,ithasbeenincidentallyobservedthat….803、Similarfindingswereobtainedinpressure‐overloadedmice,inwhichpropranololpreventeddevelopmentofLVhypertrophyandprogressiontoLVdysfunctionbutfailedtoinhibittheattendantmyocardialfibrosis.804、Afirstgoalofthepresentstudywasthereforetoreassessandmorein‐depthcharacterizetheeffectsofXXXonthecardiacstructuralalterationsassociatedwith….Asecondgoalwastotestthehypothesisthat…805、Theseissueswereaddressedinratswithaorticbanding‐inducedpressureoverloadand…806、Theresultsdisclosedthatthelatterbutnottheformer….Consideringtheseresults,athirdgoalofthestudyarose,namelytogainmechanisticinsightintothedifferentialantifibroticeffectsof…and…807、Weadditionallystudied….Atvariancewith…isevenbetterdocumentedbythe808、TheincreasedMMPactivitywasparalleledbyanincreasedTIMPconcentrationsothattheirratiowasnotsignificantlyreducedinthe…809、Ourstudystrengthensandextendsthenotionthat…810、Whichwasalmostcompletelyabrogatedin…buttotallyunaffectedinratswith…811、XXXisthustobeascribedtoadifferentinfluenceofthetwointerventionsonthemechanismscontrollingextracellularmatrixturnover812、Toourbestknowledge,therehasbeennopreviousdemonstrationthatan…2813、XXXcanshiftthebalanceofextracellularmatrixturnovertowardamarkedlyenhanced814、collagenolyticactivity,andtodosotosuchalargeextenttocompletelyoffsetthepowerfulstimulustocollagendepositionrepresentedbypressureoverload.815、Intriguingly,however,ithasbeenreportedthat….816、Althoughourstudywasnotdesignedtoexhaustivelyaddressthemechanismunderlyingthedifferentialeffectofsympathectomyand_‐blockadeoninterstitialf...
