China;Disi(临床研究)·论著··1359.临床医学工程星2023年10月第30卷第10期心宁注射液联合美托洛尔治疗冠心病心绞痛的临床效果探李婧1，李昕2（1郑州公交医院心内科，河南郑州450052；2郑州大学第二附属医院内科，河南郑州450014）【摘要】目的探讨冠心宁注射液联合美托洛尔治疗冠心病心绞痛的临床效果。方法78例冠心病心绞痛患者随机分为两组，对照组采用美托洛尔治疗，观察组采用冠心宁注射液联合美托洛尔治疗，比较两组的治疗效果。结果观察组的总有效率为94.87%，显著高于对照组的76.92%（P<0.05）。治疗后，观察组的LVEDD、LVESD、心绞痛发作频率均显著低于对照组，心绞痛发作持续时间显著短于对照组（P<0.05)。两组的不良反应总发生率比较，差异无统计学意义（P>0.05)。结论冠心宁注射液联合美托洛尔治疗冠心病心绞痛的效果显著，可明显改善患者的心功能和心绞痛发作情况，且安全性较高。【关键词】冠心病心绞痛；冠心宁注射液；美托洛尔；治疗效果；不良反应中图分类号：R2-031文献标识码：Adoi:10.3969/j.issn.1674-4659.2023.10.1359ectofGuanxinningInjectionCombinedwithMetoprololincussionontheClinicalEffectofGuanxinningInjectionConedwithMetoprololintheTreatmentofAnginaPectorisofCoronaryHeartDiseaseIlLIJing',LIXin?('DepartmentofCardiology,ZhengzhouGongjiaoHospital,Zhengzhou450052DepartmentofInternalMedicine,theSecondAffiliatedHospitalofZhengzhouUniversity,Zhengzhou450014,China)[Abstract]ObjectiveToexploretheclinicaleffectofGuanxinninginjectioncombinedwithmetoprololinthetreatmentofanginapectorisofcoronaryheartdisease.Methods78patientswithanginapectorisofcoronaryheartdiseasewererandomlydividedintotwogroups.Thecontrolgroupwastreatedwithmetoprolol,andtheobservationgroupwastreatedwithGuanxinninginjectioncombinedwithmetoprolol.Thetreatmenteffectsofthetwogroupswerecompared.ResultsThetotaleffectiverateintheobservationgroupwas94.87%,significantlyhigherthan76.92%inthecontrolgroup(P<0.05).Atertreatment,theLVEDD,LVESDandfrequencyofanginapectorisattackintheobservationgroupweresignificantlylowerthanthoseinthecontrolgroup,andthedurationofanginapectorisatackwassignificantlyshorterthanthatinthecontrolgroup(P<0.05).Nosignificantdifferencewasfoundinth...
