研究报告生命科学仪器2023第21卷/1期35基金项目：国家自然科学基金重大科研仪器研制项目(81827803，81727804)，国家自然科学基金指南引导类原创探索计划项目（82151311）国家自然科学基金(61875085，11902154)，江苏省重点研发计划(社会发展)项目（BE2020705），江苏省自然科学基金(BK20190387)通讯作者：钱志余，男，博士，南京航空航天大学，教授，E-mail:zhiyu@nuaa.edu.cn作者简介：钟旻(1999.09-)，女，硕士，E-mail:zhongmin@nuaa.edu.cnAbstract:Inordertostudythephotontransportofvisiblenear-infraredspectroscopyincervicaltissue,adouble-layercervicaltissuemodelwasconstructedaccordingtothestructureofcervicaltissue,andtheMonteCarlomethodwasusedtosimulatethelightdistributionofvisiblelight(about500nm)andnear-infraredlight(about810nm)incervicaltissue,andthedifferencesindiffusereflectance,absorbedenergydensityandlightenergyflowrateinnormalcervicaltissueandhigh-gradeprecancertissuewerestudied.Theresultsshowedthatthediffusereflectanceofnormalcervicaltissuewasgreaterthanthatofhigh-gradediseasedtissue.Intheepitheliallayer,thelightabsorptionenergydensityofnormalcervicaltissuesisgreaterthanthatofhigh-gradediseasedtissues,andthelight-absorbedenergydensityofnormalcervicaltissuesinthestromallayerissmallerthanthatofhigh-gradediseasedtissues.Thelightenergyflowrateofnormalcervicaltissuesisgreaterthanthatofhigh-gradediseasedtissues,andcomparedwithvisiblelight,NIRlighthasagreaterrangeanddeeperdetectiondepthincervicaltissue.Itprovidesatheoreticalbasisforthediagnosisofcervicalprecancerouslesionsusingvisiblenear-infraredspectroscopy.Keywords：Cervicaltissue;MonteCarloSimulation;lighttransportpropertiesStudyonthelighttransportpropertiesincervicaltissuebyMonteCarloMethodZHONGMin1,ZHANGDan1,QIANZhiyu1*(1.SchoolofAutomation,NanjingUniversityofAeronauticsandAstronautics,Nanjing,Jiangsu,211106)摘要：为研究可见近红外光谱在宫颈组织中的光子传输情况，根据宫颈组织的结构，构建双层宫颈组织模型，利用蒙特卡罗方法模拟可见光(500nm左右)和近红外光(810nm左右)在宫颈组织中的光分布，研究宫颈正常组织和高级病变组织中漫反射率、吸收能量密度、...
