36第2卷第14期2023年7月Vol.2No.14Jul.2023科技与健康TechnologyandHealth骨科Ⅰ类切口手术应用抗菌药物情况调查与分析——以定西市第二人民医院为例董治银（定西市第二人民医院药剂科，甘肃定西743000）摘要：了解骨科Ⅰ类切口手术应用抗菌药物的情况，为抗菌药物合理使用提供参考。对2021年7月—2022年6月定西市第二人民医院骨科出院的Ⅰ类切口手术病历913份进行用药情况分析。结果显示，913例Ⅰ类切口手术患者中预防性使用抗菌药物的有507例（55.53%），抗菌药物品种选择合理率为87.57%，抗菌药物品种选择占比最大的药物为注射用头孢唑林钠，占52.38%，头孢呋辛钠占25.92%。抗菌药物预防使用时机合理率为92.11%，术后24h停药率为84.42%。研究发现，骨科Ⅰ类切口手术预防性应用抗菌药物情况存在较多不合理问题，应加强处方点评，进一步促进Ⅰ类切口手术抗菌药物合理使用。关键词：骨科；Ⅰ类切口手术；抗菌药物；调查与分析中图分类号：R969.3文献标识码：AInvestigationandAnalysisofAntimicrobialDrugsAppliedtoOrthopedicClassIIncisionSurgery——TaketheSecondPeople’sHospitalofDingxiCityasanexampleDongZhiyin(DepartmentofPharmacy,SecondPeople’sHospitalofDingxi,Dingxi,Gansu743000)Abstract:UnderstandtheapplicationofantibacterialdrugsinorthopedicclassIincisionsurgery,andprovidereferencefortherationaluseofantibacterialdrugs.FromJuly2021toJune2022,913medicalrecordsofClassIincisionsurgerydischargedfromtheDepartmentofOrthopedicsoftheSecondPeople’sHospitalofDingxiCitywereanalyzed.Theresultsshowedthat507(55.53%)ofthe913patientsundergoingclassIincisionsurgeryhadprophylacticantibacterialdrugs,therationalityrateofantibacterialdrugselectionwas87.57%,thedrugwiththelargestproportionofantibacterialdrugselectionwascefazolinsodiumforinjection,accountingfor52.38%,andcefuroximesodiumaccountedfor25.92%.Thereasonablerateofantibacterialdrugpreventionwas92.11%,andthewithdrawalrate24hoursaftersurgerywas84.42%.ThestudyfoundthatthereweremanyunreasonableproblemsinthepreventiveapplicationofantibacterialdrugsinorthopedicclassIincisionsurgery,andprescriptionreviewsshouldbestrengthenedtofurtherpromotetherationaluseofantibacterialdrugsinclassIincisionsurgery.Keywords...
