JournalPre-proofSingle-cellgenomicsandspatialtranscriptomics:discoveryofnovelcellstatesandcellularinteractionsinliverphysiologyanddiseasebiologyAntonioSaviano,NeilC.Henderson,ThomasF.BaumertPII:S0168-8278(20)30372-XDOI:https://doi.org/10.1016/j.jhep.2020.06.004Reference:JHEPAT7794Toappearin:JournalofHepatologyReceivedDate:31January2020RevisedDate:28May2020AcceptedDate:2June2020Pleasecitethisarticleas:SavianoA,HendersonNC,BaumertTF,Single-cellgenomicsandspatialtranscriptomics:discoveryofnovelcellstatesandcellularinteractionsinliverphysiologyanddiseasebiology,JournalofHepatology(2020),doi:https://doi.org/10.1016/j.jhep.2020.06.004.ThisisaPDFfileofanarticlethathasundergoneenhancementsafteracceptance,suchastheadditionofacoverpageandmetadata,andformattingforreadability,butitisnotyetthedefinitiveversionofrecord.Thisversionwillundergoadditionalcopyediting,typesettingandreviewbeforeitispublishedinitsfinalform,butweareprovidingthisversiontogiveearlyvisibilityofthearticle.Pleasenotethat,duringtheproductionprocess,errorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.©2020EuropeanAssociationfortheStudyoftheLiver.PublishedbyElsevierB.V.1Single-cellgenomicsandspatialtranscriptomics:discoveryofnovelcellstatesandcellularinteractionsinliverphysiologyanddiseasebiologyAntonioSaviano1,2,3,NeilC.Henderson4,5§,ThomasF.Baumert1,2,3,6§1Inserm,U1110,InstitutdeRecherchesurlesMaladiesViralesetHépatiques,Strasbourg,France2UniversitédeStrasbourg,Strasbourg,France3PôleHépato-digestif,Institut-Hospitalo-Universitaire,HôpitauxUniversitairesdeStrasbourg,Strasbourg,France4CentreforInflammationResearch,UniversityofEdinburgh,EdinburghEH164TJ,UK5MRCHumanGeneticsUnit,InstituteofGeneticsandMolecularMedicine,UniversityofEdinburgh,EdinburghEH42XU,UK6InstitutUniversitairedeFrance,Paris,France.§Correspondenceshouldbeaddressedto:Prof.ThomasF.Baumert,MD,InsermU1110,InstitutdeRecherchesurlesMaladiesViralesetHépatiques,UniversitédeStrasbourg,3rueKoeberl...