KinasePhosphataseTranscriptionFactorCaspaseReceptorEnzymepro-apoptoticpro-survivalGAP/GEFGTPaseG-proteinAcetylaseDeacetylaseRibosomalsubunitDirectStimulatoryModificationDirectInhibitoryModificationMultistepStimulatoryModificationMultistepInhibitoryModificationTentativeStimulatoryModificationTentativeInhibitoryModificationSeparationofSubunitsorCleavageProductsJoiningofSubunitsTranslocationTranscriptionalStimulatoryModificationTranscriptionalInhibitoryModificationCELLSIGNALINGTECHNOLOGYwww.cellsignal.comPathwayDiagramKeys48S43S40S60S40S60S40S60SeIF5BeIF6eIF3eIF1eIF1AeIF5eIF2-GDPPABPeIF4FeIF2-GTPMet-tRNAeIF1AeIF1eIF5eIF3ERF1GSPTeEF1eEF2eEF2KeIF4B40S60S48SeIF4Control:GrowthFactors,Hormones,Cytokines,Mitogens,Neuropeptides,OxidativeStresseEF2Control:Ca2+cAMPmTORC1InitiationStressGranulesP-bodiesONeIF2Control:ViralInfection(dsRNA),(PKR)AminoAcidStarvation,(GCN2)HemeDeficiency,(HRI)HeatShock,(PERK)ERStress,(PERK)Hypoxia(PERK),UVLight,(GCN2)OFFElongationNascentPolypeptideA(n)CapAUGCapPolypeptideChainFactorReleaseScanningEncounterAUGERLumenTerminationA(n)AUGA(n)CapAUGA(n)AUGA(n)CapCapAUGAAAAACapInitiationComplexTranslationalControl:Overview©2002–2014CellSignalingTechnology,Inc.
