Atg11Atg11Atg11Atg19Atg19Atg19Atg19Atg11Atg19Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg8Atg19Atg19prApe1Ape1complexAms1CVTPATHWAYAtg19PEXOPHAGYAtg8Atg8Atg8Atg8Atg8Atg8Atg11Pex3Pex3PpPex3PpPex14PpAtg11Atg36Atg36PpAtg30PpAtg30PpAtg8PpAtg8PpAtg8PpAtg8PpAtg8PpAtg8PpAtg17Atg8Atg8Atg8Atg8Atg8Atg8Atg11Atg11Atg11MITOPHAGYAtg32Atg32Atg32Atg32Atg32FUNGIMAMMALSMAMMALSMAMMALSMAMMALSFUNGIFUNGICMAKFERQHSPA8lys-HSPA8LAMP2APINK1PARK2SQSTM1LC3LC3LC3LC3LC3LC3BNIP3LBNIP3LSQSTM1LC3MITOPHAGYSQSTM1LC3LC3LC3LC3LC3LC3UbUbPINK1PARK2UbLC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3XENOPHAGYUbUbUbUbUbCALCOCO2OPTNOPTNSQSTM1SQSTM1UbLC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3PEXOPHAGYPEX14PEX14SQSTM1SQSTM1LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3LC3UbUbUbCargoLigandScaffoldReceptorAtg8Atg8Atg8Atg8Atg8Atg8MODELAtg8Atg8PhagophoreAutophagosomeEndosomalmicroautophagySelectivemacroautophagySelectivemicroautophagyNonselectivemacroautophagyChaperone-mediatedautophagyLysosome/vacuoleMultivesicularbodySnapShot:SelectiveAutophagyMeiyanJin,XuLiu,andDanielJ.KlionskyLifeSciencesInstituteandtheDepartmentofMolecular,Cellular,andDevelopmentalBiology,UniversityofMichigan,AnnArbor,MI48109,USASeeonlineversionforlegendandreferences.PROcesscARGO(LIGAnD)RecePTORscAffOLDReLATeDDefecTsfungiCvtpathwayApe1(propeptide),Ape4,Ams1Atg19Atg11MitophagyMitochondriaAtg32Atg11Metabolicdisorder,DNAdamageMicronucleophagyPortionsofnucleus(Nvj1)Vac8-PexophagyPeroxisomes(Pex3/PpPex3,PpPex14)PpAtg30,Atg36Atg11/PpAtg11,PpAtg17FungalinfectionReticulophagyERfragments-Atg11ERstress,lossofviabilityRibophagyRibosomes(Rpl25-Ub)--WormsAggrephagyPgranulecomponentsSEPA-1EPG-2EmbryogenesisMammalsAggrephagyMisfoldedproteins(Ub)SQSTM1,NBR1WDFY3Cancer,neurodegenerationCMACargoprotein(KFERQmotif)LAMP2A-Kidneydiseases,lysosomalstoragedisorders,neurodegenerationGlycophagyGlycogengranulesSTBD1Lysosomalstoragedisorders,myopathiesLipophagyLipiddroplets--Liverdiseases,metabolicdisordersMidbophagyMidbodyrings(CEP55)NBR1,SQSTM1-CancerMitophagyMitochondria(Ub)SQSTM1,BNIP3L-Par...
