Page1of28Thyroid©MaryAnnLiebert,Inc.DOI:10.1089/thy.2018.02121ThyroidTheJAK/STAT3andNF-κBsignalingpathwaysregulatecancerstemcellpropertiesinanaplasticthyroidcancercells.(DOI:10.1089/thy.2018.0212)Thispaperhasbeenpeer-reviewedandacceptedforpublication,buthasyettoundergocopyeditingandproofcorrection.Thefinalpublishedversionmaydifferfromthisproof.TheJAK/STAT3andNF-Bsignalingpathwaysregulatecancerstemcellpropertiesinanaplasticthyroidcancercells.KenShiraiwa1,4,MichikoMatsuse1,YukaNakazawa2,TomooOgi2,KeijiSuzuki1,VladimirSaenko3,ShuhangXu1,KazuoUmezawa5,ShunichiYamashita1,KazuhiroTsukamoto4,NorisatoMitsutake11DepartmentsofRadiationMedicalSciences,2GenomeRepair,3RadiationMolecularEpidemiology,AtomicBombDiseaseInstitute,NagasakiUniversity.4DepartmentofPharmacotherapeutics,NagasakiUniversityGraduateSchoolofBiomedicalSciences.5DepartmentofMolecularTargetMedicine,AichiMedicalUniversitySchoolofMedicineKenShiraiwa,MSDepartmentofRadiationMedicalSciences,AtomicBombDiseaseInstitute,NagasakiUniversity.1-12-4Sakamoto,Nagasaki852-8523,Japan.DepartmentofPharmacotherapeutics,NagasakiUniversityGraduateSchoolofBiomedicalSciences.1-7-1Sakamoto,Nagasaki852-8501,Japaneine.kleine.nachtmusik.k525@gmail.comMichikoMatsuse,PhDDepartmentofRadiationMedicalSciences,AtomicBombDiseaseInstitute,NagasakiUniversity.1-12-4Sakamoto,Nagasaki852-8523,Japan.michikom@nagasaki-u.ac.jpYukaNakazawa,PhDDepartmentofGenomeRepair,AtomicBombDiseaseInstitute,NagasakiUniversity.1-12-4Sakamoto,Nagasaki852-8523,Japan.Currentaddress:DepartmentofGenetics,ResearchInstituteofEnvironmentalMedicine,NagoyaUniversity.Furo-cho,Chikusa-ku,Nagoya464-8601,Japanyu-naka@riem.nagoya-u.ac.jpDownloadedbyMIDWESTERNUNIVERSITYMULTISITEfromwww.liebertpub.comat02/21/19.Forpersonaluseonly.Page2of282ThyroidTheJAK/STAT3andNF-κBsignalingpathwaysregulatecancerstemcellpropertiesinanaplasticthyroidcancercells.(DOI:10.1089/thy.2018.0212)Thispaperhasbeenpeer-reviewedandacceptedforpublication,buthasyettoundergocopyeditingandproofcorrection.Thefi...
