JournalPre-proofTumormicroenvironmentandepithelialmesenchymaltransitionastargetstoovercometumormultidrugresistanceNurayErin,JelenaGrahovac,AnamariaBrozovic,ThomasEfferthPII:S1368-7646(20)30044-3DOI:https://doi.org/10.1016/j.drup.2020.100715Reference:YDRUP100715Toappearin:DrugResistanceUpdatesReceivedDate:15November2019RevisedDate:29May2020AcceptedDate:7June2020Pleasecitethisarticleas:ErinN,GrahovacJ,BrozovicA,EfferthT,Tumormicroenvironmentandepithelialmesenchymaltransitionastargetstoovercometumormultidrugresistance,DrugResistanceUpdates(2020),doi:https://doi.org/10.1016/j.drup.2020.100715ThisisaPDFfileofanarticlethathasundergoneenhancementsafteracceptance,suchastheadditionofacoverpageandmetadata,andformattingforreadability,butitisnotyetthedefinitiveversionofrecord.Thisversionwillundergoadditionalcopyediting,typesettingandreviewbeforeitispublishedinitsfinalform,butweareprovidingthisversiontogiveearlyvisibilityofthearticle.Pleasenotethat,duringtheproductionprocess,errorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.©2020PublishedbyElsevier.1TumormicroenvironmentandepithelialmesenchymaltransitionastargetstoovercometumormultidrugresistanceNurayErin1,JelenaGrahovac2,AnamariaBrozovic3,andThomasEfferth41DepartmentofPharmacology,SchoolofMedicine,Antalya,Turkey2LaboratoryforExperimentalPharmacology,InstituteforOncologyandRadiologyofSerbia,Belgrade,Serbia3DivisionofMolecularBiology,RuđerBoškovićInstitute,Zagreb,Croatia.4DepartmentofPharmaceuticalBiology,InstituteofPharmacyandBiochemistry,JohannesGutenbergUniversity,Mainz,GermanyCorrespondingauthor:NurayErinDepartmentofMedicalPharmacology,SchoolofMedicine,AkdenizUniversityB-blokkat1ImmunolojiAntalya07070,TurkeyEmail:nerin@akdeniz.edu.trPhone24222496159ORCID:0000-0002-6116-1970Runningtitle:TumormicroenvironmentandovercomingchemoresistanceAbstractItiswellestablishedthatmultifactorialdrugresistancehinderssuccessfulcancertreatment.Tumorcellinteractionswiththetumormicroenvironme...
