AcceptedManuscriptExtrinsicandintrinsicmechanismsbywhichmesenchymalstemcellssuppresstheimmunesystemVivienJ.Coulson-Thomas,PhD,YvetteM.Coulson-Thomas,PhD,TarsisF.Gesteira,PhD,WinstonW.-Y.Kao,PhDPII:S1542-0124(15)00207-4DOI:10.1016/j.jtos.2015.11.004Reference:JTOS157Toappearin:OcularSurfaceReceivedDate:28May2015RevisedDate:12November2015AcceptedDate:23November2015Pleasecitethisarticleas:Coulson-ThomasVJ,Coulson-ThomasYM,GesteiraTF,KaoWW-Y,Extrinsicandintrinsicmechanismsbywhichmesenchymalstemcellssuppresstheimmunesystem,OcularSurface(2016),doi:10.1016/j.jtos.2015.11.004.ThisisaPDFfileofanuneditedmanuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomersweareprovidingthisearlyversionofthemanuscript.Themanuscriptwillundergocopyediting,typesetting,andreviewoftheresultingproofbeforeitispublishedinitsfinalform.Pleasenotethatduringtheproductionprocesserrorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.MANUSCRIPTACCEPTEDACCEPTEDMANUSCRIPT1TITLE:ExtrinsicandintrinsicmechanismsbywhichmesenchymalstemcellssuppresstheimmunesystemAUTHORS:VivienJ.Coulson-Thomas,PhD,1,2,*YvetteM.Coulson-Thomas,PhD,3TarsisF.Gesteira,PhD,1andWinstonW.-Y.Kao,PhD1,*SHORTTITLE:MESENCHYMALSTEMCELLSSUPPRESSIMMUNERESPONSE/Coulson-Thomas,etalFOOTNOTESAcceptedforpublicationNovember2015.From1DepartmentofOphthalmology,UniversityofCincinnati,Ohio,USA,2JohnvanGeestCentreforBrainRepair,UniversityofCambridge,Cambridge,UK,3DepartamentodeBioquímica,UniversidadeFederaldeSãoPaulo,SãoPaulo,SP,Brazil.ThereviewwasinpartsupportedbyNIH/NEIgrant1R01EY021768,ResearchtoPreventBlindness,OhioLionsEyeResearchFoundation,ConselhoNacionaldeDesenvolvimentoCientificoeTecnológico(CNPq)andCoordenaçãodeAperfeiçoamentodePessoaldeNível(CAPES).Theauthorshavenocommercialorproprietaryinterestinanyconceptorproductdiscussedinthisarticle.Single-copyreprintrequeststoV.J.Coulson-Thomas,PhD,orWinstonW-YKao,PhD(addressbelow).Correspondingauthors:VivienJ.Coulson-ThomasandWinstonW-YKao...