AcceptedManuscriptLongNoncodingRNAuc.173PromotesRenewaloftheIntestinalMucosabyInducingDegradationofMicroRNA195LanXiao,JingWu,Jun-YaoWang,HeeKyoungChung,SudhakarKalakonda,JaladankiN.Rao,MyriamGorospe,Jian-YingWangPII:S0016-5085(17)36250-9DOI:10.1053/j.gastro.2017.10.009Reference:YGAST61483Toappearin:GastroenterologyAcceptedDate:7October2017Pleasecitethisarticleas:XiaoL,WuJ,WangJ-Y,ChungHK,KalakondaS,RaoJN,GorospeM,WangJ-Y,LongNoncodingRNAuc.173PromotesRenewaloftheIntestinalMucosabyInducingDegradationofMicroRNA195,Gastroenterology(2017),doi:10.1053/j.gastro.2017.10.009.ThisisaPDFfileofanuneditedmanuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomersweareprovidingthisearlyversionofthemanuscript.Themanuscriptwillundergocopyediting,typesetting,andreviewoftheresultingproofbeforeitispublishedinitsfinalform.Pleasenotethatduringtheproductionprocesserrorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.MANUSCRIPTACCEPTEDACCEPTEDMANUSCRIPTMs.GASTRO-D-17-00987,R1Revised9-16-20171LongNoncodingRNAuc.173PromotesRenewaloftheIntestinalMucosabyInducingDegradationofMicroRNA195LanXiao,a,bJingWu,a,bJun-YaoWang,a,bHeeKyoungChung,a,bSudhakarKalakonda,a,bJaladankiN.Rao,a,bMyriamGorospe,candJian-YingWanga,b,d*aCellBiologyGroup,DepartmentofSurgery,anddDepartmentofPathology,UniversityofMarylandSchoolofMedicine,andbBaltimoreVeteransAffairsMedicalCenter,Maryland21201;andcLaboratoryofGeneticsandGenomics,NationalInstituteonAging-IRP,NIH,Baltimore,Maryland21224RunningTitle:LncRNAuc.173promotesgutmucosalgrowthSubmittedto:GastroenterologyAuthorContributions:L.X.andJ.W.performedmostexperimentsandsummarizeddata.J.Y.W.,H.K.C,andS.K.performedexperimentsinvivoandbiotinpull-downassays.J.N.R.performedexperimentsregardingmiR-195promoter.M.G.contributedtoexperimentaldesignanddataanalysis.J.Y.W.designedexperiments,analyzeddata,preparedfigures,anddraftedthemanuscript.Abbreviationsused:LncRNA,longnoncodingRNA;T-UCRs,transcribedultraconservedregions;IEC...
