ContentslistsavailableatScienceDirectAgeingResearchReviewsjournalhomepage:www.elsevier.com/locate/arrReviewDNAdamagerepairresponseinmesenchymalstromalcells:FromcellularsenescenceandagingtoapoptosisanddifferentiationabilityBehnazbanimohamad-shotorbania,g,1,HoumanKahrobab,c,d,l,*,HadiSadeghzadehb,g,1,DavidMWilsonIIIh,HamidMaadii,NasserSamadid,e,MohammadSaeidHejazic,d,f,HekmatFarajpourj,BehzadNematiOnarik,MohammadRezaSadeghid,*aDrugAppliedResearchCenter,TabrizUniversityofMedicalSciences,Tabriz,IranbBiotechnologyResearchCenter,TabrizUniversityofMedicalSciences,Tabriz,IrancMolecularMedicineResearchCenter,TabrizUniversityofMedicalSciences,Tabriz,IrandDepartmentofMolecularMedicine,FacultyofAdvancedMedicalSciences,TabrizUniversityofMedicalSciences,Tabriz,IraneDepartmentofBiochemistry,FacultyofMedicine,TabrizUniversityofMedicalSciences,Tabriz,IranfDepartmentofPharmaceuticalBiotechnology,FacultyofPharmacy,TabrizUniversityofMedicalSciences,Tabriz,IrangTissueEngineeringDepartment,FacultyofAdvancedMedicalSciences,TabrizUniversityofMedicalSciences,Tabriz,IranhHasseltUniversity,BiomedicalResearchInstitute,Diepenbeek,BelgiumiDepartmentofMedicalGenetics,andSignalTransductionResearchGroup,FacultyofMedicineandDentistry,UniversityofAlberta,Edmonton,ABT6G2H7,CanadajDepartmentofTissueEngineeringandAppliedCellSciences,SchoolofAdvancedTechnologiesinMedicine,ShahidBeheshtiUniversityofMedicalSciences,Tehran,IrankDepartmentofNeurology,SchoolofMedicine,ArdabilUniversityofMedicalSciences,Ardabil,IranlStudentsResearchCommittee,TabrizUniversityofMedicalSciences,Tabriz,IranARTICLEINFOKeywords:MalignancyBaseexcisionrepairNucleotideexcisionrepairHomologousrecombinationNon-homologousendjoiningMismatchrepairABSTRACTMesenchymalstromalcells(MSCs)areheterogeneousandcontainseveralpopulations,includingstemcells.MSCs'secretomehastheabilitytoinduceproliferation,differentiation,chemo-attraction,anti-apoptosis,andimmunomodulationactivitiesinstemcells.Moreover,thesecellsrecognizetissuedamagecausedbydrugs,rad...
