SnapShot:ChromatinRemodelingComplexesYunheBaoandXuetongShenDepartmentofCarcinogenesis,M.D.AndersonCancerCenter,Smithville,TX78957,USAINO80SubfamilyINO80SWR1SpeciesYeastFlyHumanYeastHumanFlyHumanYeastComplexINO80Pho-dINO80INO80SWR1SRCAPTip60TRRAP/Tip60NuA4HomologoussubunitsaIno80dIno80hIno80Swr1SRCAPDominoP400Rvb1,Rvb2Reptin,PontinTip49a,Tip49bRvb1,Rvb2Tip49a,Tip49bReptin,PontinTip49a,Tip49bArp4,5,8,Act1dArp5,8,dActinBAF53a,Arp5,8Arp4,6,Act1BAF53a,Arp6BAP55,Act87EBAF53a,ActinArp4,Act1Taf14Yaf9GAS41dGAS41GAS41Yaf9Ies2hIes2Ies6hIes6Swc4/Eaf2DMAP1dDMAP1DMAP1Swc4/Eaf2Swc2/Vps72YL-1dYL-1YL-1Bdf1dBrd8Brd8/TRCp120H2AZ,H2BH2AZ,H2BH2Av,H2BSwc6/Vps71ZnF-HIT1dTra1TRRAPTra1dTIP60Tip60Esa1dMRG15MRG15,MRGXEaf3dEaf6FLJ11730Eaf6dMRGBPMRGBPEaf7E(Pc)EPC1,EPC-likeEpl1dING3ING3Yng2UniquesubunitsIes1,Ies3-5,Nhp10PhoAmida,NFRKB,MCRS1,FLJ90652,FLJ20309Swc3,5,7Eaf5,Eaf1/Vid21ISWISubfamilyACF/CHRACNURFSpeciesYeastYeastYeastFlyHumanFlyHumanComplexISW1aISW1bISW2bACFcACFdNURFNURFHomologoussubunitsaIsw1Isw1Isw2ISWIhSNF2HISWIhSNF2LItc1ACF1WCRF180/hACF1NURF301BPTFNURF55/p55RbAP46,RbAP48UniquesubunitsIoc3Ioc2,Ioc4NURF38Mi-2/CHDSubfamilyCHD1Mi-2/CHDSpeciesYeastFlyHumanFlyHumanComplexCHD1CHD1CHD1Mi-2/NuRDNuRDgHomologoussubunitsaChd1dCHD1CHD1dMi-2Mi-2α/CHD3,Mi-2β/CHD4dMBD2/3MBD3dMTAMTA1,2,3dRPD3HDAC1,2p55RbAp46,48p66/68p66α,βUniquesubunitsDOC-1?SWI/SNFSubfamilySWI/SNFSpeciesYeastYeastFlyHumanComplexSWI/SNFRSCBAPeBAFfHomologoussubunitsaSwi2/Snf2Sth1BRMBRG1orhBRMSwi1/Adr6OSA/eyelidBAF250/hOSA1Rsc1orRsc2,Rsc4Swi3Rsc8MOR/BAP155BAF155,BAF170Swp73Rsc6BAP60BAF60aArp7,Arp9Arp7,Arp9BAP55,BAP47BAF53Snf5Sfh1SNR1/BAP45hSNF5BAP111/dalaoBAF57β-actinβ-actinUniquesubunitsSwp82,Taf14,Snf6,Snf11Rsc3,5,7,9,10,30,Htl1,Ldb7,andRtt102INO80regulatestranscriptionandisinvolvedinDNArepairandcell-cyclecheckpointadaptation.IthasATP-dependentnucleosomemobi-lizationactivityinvitro.SWR1regulatestranscriptionandisalsoinvolvedindepositionofhis-toneH2AZ,chromosomestability,andcell-cyclecheckpointadaptation.Invitroitcanreplace...
