LncPRESS1isap53-regulatedlncRNAthatsafeguardspluripotencybydisruptingSIRT6mediatedde-acetylationofhistoneH3K56AbhinavKJain1,2,3,ψ,YuanxinXi4,RyanMcCarthy1,2,3,KendraAllton1,2,3,KadirCAkdemir5,LalitRPatel1,8,BruceAronow6,ChunruLin7,WeiLi4,LiuqingYang7,andMichelleCBarton1,2,3,8,ψ,♯1DepartmentofEpigenetics&MolecularCarcinogenesis,TheUniversityofTexasMDAndersonCancerCenter,Houston,TX,USA770302CenterforStemCell&DevelopmentBiology,TheUniversityofTexasMDAndersonCancerCenter,Houston,TX,USA770303CenterforCancerEpigenetics,TheUniversityofTexasMDAndersonCancerCenter,Houston,TX,USA770304DanL.DuncanCancerCenter,DepartmentofMolecular&CellularBiology,BaylorCollegeofMedicine,Houston,TX,USA770305DepartmentofGenomicMedicine,TheUniversityofTexasMDAndersonCancerCenter,Houston,TX,USA770306DivisionofBiomedicalInformatics,DepartmentofPediatrics,CincinnatiChildren’sHospitalMedicalCenter,Cincinnati,OH,USA452297DepartmentofMolecular&CellularOncology,TheUniversityofTexasMDAndersonCancerCenter,Houston,TX,USA77030ψTowhomcorrespondenceshouldbeaddressed:MichelleC.Barton,PhD,DepartmentofEpigenetics&Molecular,Carcinogenesis,TheUniversityofTexasMDAnderson,CancerCenter,1515HolcombeBlvd,Unit1000,Houston,TX-77030,Ph:713-834-6268,FAX:713-834-6273,mbarton@mdanderson.org;AbhinavK.Jain,PhD,DepartmentofEpigenetics&Molecular,Carcinogenesis,TheUniversityofTexasMDAnderson,CancerCenter,1515HolcombeBlvd,Unit1000,Houston,TX-77030,Ph:713-834-6271,FAX:713-834-6273,ajain@mdanderson.org.♯LeadContactPublisher'sDisclaimer:ThisisaPDFfileofanuneditedmanuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomersweareprovidingthisearlyversionofthemanuscript.Themanuscriptwillundergocopyediting,typesetting,andreviewoftheresultingproofbeforeitispublishedinitsfinalcitableform.Pleasenotethatduringtheproductionprocesserrorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertain.AccessionNumbersRNA-SeqexpressiondatacanbeaccessedatNCBIGeneExpressionOmnibus(GEO)(http://www.ncbi.nl...
